| URN | urn:agi-llid:29302 |
|---|---|
| Connectivity | 23 |
| Name | Itgb |
| Description | integrin beta |
| Notes | beta chain of integrin; involved in cardiac remodeling after myocardial infarction [RGD] |
| Pathway | integrin mediated signaling pathway |
|---|---|
| integrin mediated signaling pathway | |
| integrin mediated signaling pathway | |
| integrin mediated signaling pathway |
| GO Molecular Function | peptide binding |
|---|---|
| cell adhesion molecule binding | |
| fibrinogen binding | |
| protein heterodimerization activity | |
| vascular endothelial growth factor receptor 2 binding | |
| receptor activity |
| GO Cellular Component | cell surface |
|---|---|
| membrane | |
| plasma membrane | |
| platelet alpha granule membrane | |
| membrane fraction | |
| integrin complex | |
| integral to membrane |
| GO Biological Process | cell adhesion |
|---|---|
| negative regulation of lipid storage | |
| negative regulation of macrophage derived foam cell differentiation | |
| positive regulation of MAPKKK cascade | |
| negative regulation of lipoprotein metabolic process | |
| negative regulation of low-density lipoprotein receptor biosynthetic process | |
| positive regulation of peptidyl-tyrosine phosphorylation | |
| activation of protein kinase activity | |
| positive regulation of endothelial cell proliferation | |
| positive regulation of endothelial cell migration | |
| positive regulation of leukocyte migration | |
| smooth muscle cell migration | |
| cell-matrix adhesion | |
| platelet aggregation | |
| cellular calcium ion homeostasis | |
| regulation of G-protein coupled receptor protein signaling pathway | |
| negative regulation of lipid transport | |
| integrin-mediated signaling pathway |
| Group | cell adhesion |
|---|---|
| negative regulation of lipid storage | |
| negative regulation of macrophage derived foam cell differentiation | |
| positive regulation of MAPKKK cascade | |
| negative regulation of lipoprotein metabolic process | |
| negative regulation of low-density lipoprotein receptor biosynthetic process | |
| positive regulation of peptidyl-tyrosine phosphorylation | |
| activation of protein kinase activity | |
| positive regulation of endothelial cell proliferation | |
| positive regulation of endothelial cell migration | |
| positive regulation of leukocyte migration | |
| smooth muscle cell migration | |
| cell-matrix adhesion | |
| platelet aggregation | |
| cellular calcium ion homeostasis | |
| regulation of G-protein coupled receptor protein signaling pathway | |
| negative regulation of lipid transport | |
| integrin-mediated signaling pathway | |
| peptide binding | |
| cell adhesion molecule binding | |
| fibrinogen binding | |
| protein heterodimerization activity | |
| vascular endothelial growth factor receptor 2 binding | |
| receptor activity | |
| cell surface | |
| membrane | |
| plasma membrane | |
| platelet alpha granule membrane | |
| membrane fraction | |
| integrin complex | |
| integral to membrane |
| MedScan ID | 29302 |
|---|
| LocusLink ID | 29302 |
|---|
| Alias | integrin, beta 3 |
|---|---|
| integrin beta 3 (Cd61) | |
| itgb3 | |
| integrin beta 3 |
| Organism | Rattus norvegicus |
|---|
| GenBank ID | NW_001084656 |
|---|---|
| NM_153720 | |
| NP_714942 | |
| AC_000078 | |
| AJ440952 | |
| CAD29521 | |
| Q8R2H2 |
| GO ID | 0050839 |
|---|---|
| 0070051 | |
| 0042277 | |
| 0046982 | |
| 0004872 | |
| 0043184 | |
| 0032147 | |
| 0007155 | |
| 0007160 | |
| 0006874 | |
| 0007229 | |
| 0010888 | |
| 0032369 | |
| 0050748 | |
| 0045715 | |
| 0010745 | |
| 0070527 | |
| 0043410 | |
| 0010595 | |
| 0001938 | |
| 0002687 | |
| 0050731 | |
| 0008277 | |
| 0014909 | |
| 0009986 | |
| 0016021 | |
| 0008305 | |
| 0016020 | |
| 0005624 | |
| 0005886 | |
| 0031092 | |
| 0042802 | |
| 0005178 | |
| 0005515 | |
| 0007044 | |
| 0030334 | |
| 0009897 | |
| 0007275 | |
| 0016491 | |
| 0007596 | |
| 0008152 | |
| 0005737 | |
| 0005615 |
| Swiss-Prot Accession | Q8R2H2 |
|---|
| PIR ID | PN0509 |
|---|
| Unigene ID | Rn.162202 |
|---|
| KEGG ID | rno:29302 |
|---|
| Swiss-Prot ID | Q8R2H2_RAT |
|---|
| Cell Localization | Membrane |
|---|
| IPI ID | IPI00198695 |
|---|
| ListLink | http://rgd.mcw.edu/wg/home/pathway2/molecular-pathways2/integrin-beta-subunits |
|---|