| URN | urn:agi-llid:2170 |
|---|---|
| Connectivity | 91 |
| Name | Fabp3 |
| Description | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
| Notes | The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq] |
| Pathway | integrin mediated signaling pathway |
|---|
| GO Molecular Function | transporter activity |
|---|---|
| lipid binding | |
| fatty acid binding | |
| icosatetraenoic acid binding | |
| long-chain fatty acid transporter activity |
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol | |
| mitochondrion | |
| sarcoplasm | |
| sarcoplasmic reticulum |
| GO Biological Process | negative regulation of cell proliferation |
|---|---|
| transport | |
| fatty acid metabolic process | |
| phosphatidylcholine biosynthetic process | |
| fatty acid beta-oxidation | |
| response to drug | |
| response to fatty acid | |
| response to insulin stimulus | |
| long-chain fatty acid transport |
| Ariadne Ontology | Lipid transport |
|---|
| Group | Lipid transport |
|---|---|
| transporter activity | |
| negative regulation of cell proliferation | |
| transport | |
| fatty acid metabolic process | |
| phosphatidylcholine biosynthetic process | |
| fatty acid beta-oxidation | |
| response to drug | |
| response to fatty acid | |
| response to insulin stimulus | |
| long-chain fatty acid transport | |
| lipid binding | |
| fatty acid binding | |
| icosatetraenoic acid binding | |
| long-chain fatty acid transporter activity | |
| cytoplasm | |
| cytosol | |
| mitochondrion | |
| sarcoplasm | |
| sarcoplasmic reticulum |
| MedScan ID | 2170 |
|---|
| Hugo ID | 3557 |
|---|
| Human chromosome position | 1p33-p32 |
|---|
| LocusLink ID | 2170 |
|---|---|
| 14077 | |
| 79131 |
| Alias | MDGI |
|---|---|
| FABP11 | |
| H-FABP | |
| O-FABP | |
| fatty acid-binding protein, heart | |
| M-FABP | |
| fatty acid binding protein 11 | |
| mammary-derived growth inhibitor | |
| muscle fatty acid-binding protein | |
| Fatty acid-binding protein 3, muscle | |
| heart-type fatty acid-binding protein | |
| Fabph1 | |
| Fabph4 | |
| Fabph-1 | |
| Fabph-4 | |
| RP23-462N15.1 | |
| OTTMUSP00000009984 | |
| fatty acid-binding protein 3 | |
| fatty acid binding protein heart 1 | |
| fatty acid binding protein heart 4 | |
| heart fatty acid binding protein | |
| Fatty acid binding protein 3 heart | |
| Fabp3 | |
| Fabph I | |
| fatty acid binding protein 3 | |
| fatty acid binding protein 3, muscle and heart | |
| fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | |
| fatty acid binding protein heart I | |
| fatty acid binding protein heart IV | |
| fatty acid binding protein III | |
| Fatty acid-binding protein, heart (H-FABP) | |
| H FABP | |
| H(FABP) | |
| heart fatty acid-binding protein | |
| HFABP | |
| Muscle fatty acid binding protein | |
| muscle Fatty acid-binding protein 3 | |
| muscle Fatty acid-binding protein III | |
| OTTHUMP00000003898 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 134651 |
|---|
| Mouse chromosome position | 4 61.0 cM |
|---|
| GO ID | 0005504 |
|---|---|
| 0050543 | |
| 0008289 | |
| 0005324 | |
| 0005215 | |
| 0006631 | |
| 0008285 | |
| 0006656 | |
| 0042493 | |
| 0070542 | |
| 0032868 | |
| 0005829 | |
| 0016528 | |
| 0015909 | |
| 0006810 | |
| 0005737 | |
| 0005739 | |
| 0016529 | |
| 0006635 |
| Rat chromosome position | 5q36 |
|---|
| Swiss-Prot Accession | P05413 |
|---|---|
| Q6IBD7 | |
| P11404 | |
| Q5EBJ0 | |
| P07483 | |
| Q91W23 | |
| Q9QY04 | |
| B2RAB6 | |
| Q5VV93 | |
| Q99957 |
| PIR ID | PC4011 |
|---|---|
| A28458 | |
| S15432 |
| Unigene ID | Hs.657242 |
|---|---|
| Mm.388886 | |
| Rn.32566 |
| KEGG ID | hsa:2170 |
|---|---|
| mmu:14077 | |
| rno:79131 |
| Swiss-Prot ID | FABPH_MOUSE |
|---|---|
| FABPH_RAT | |
| FABPH_HUMAN | |
| Q5EBJ0_MOUSE | |
| B2RAB6_HUMAN |
| Cell Localization | Cytoplasm |
|---|---|
| Plasma membrane |
| IPI ID | IPI00230124 |
|---|---|
| IPI00231971 | |
| IPI00219684 |
| Homologene ID | 68379 |
|---|
| RGD ID | 69048 |
|---|
| MGI ID | 95476 |
|---|