| URN | urn:agi-llid:55679 |
|---|---|
| Connectivity | 11 |
| Name | Lims2 |
| Description | LIM and senescent cell antigen like domains 2 |
| Notes | LIMS2 is a focal adhesion protein that associates with integrin-linked kinase (ILK; MIM 602366), a multidomain protein that mediates multiple protein-protein interactions at adhesion sites between cells and the extracellular matrix (ECM).[supplied by OMIM] |
| Pathway | integrin mediated signaling pathway |
|---|---|
| integrin mediated signaling pathway | |
| integrin mediated signaling pathway | |
| integrin mediated signaling pathway |
| GO Molecular Function | metal ion binding |
|---|---|
| zinc ion binding |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane | |
| cytosol | |
| nucleus | |
| cell junction | |
| focal adhesion |
| Ariadne Ontology | Focal junction assembly |
|---|
| Group | Focal junction assembly |
|---|---|
| metal ion binding | |
| zinc ion binding | |
| membrane | |
| plasma membrane | |
| cytosol | |
| nucleus | |
| cell junction | |
| focal adhesion |
| MedScan ID | 55679 |
|---|
| Hugo ID | 16084 |
|---|
| Human chromosome position | 2q14.3 |
|---|
| LocusLink ID | 55679 |
|---|---|
| 225341 | |
| 361303 |
| Alias | PINCH2 |
|---|---|
| FLJ10044 | |
| LIM and senescent cell antigen-like-containing domain protein 2 | |
| PINCH-2 | |
| LIM-like protein 2 | |
| OTTHUMP00000203850 | |
| OTTHUMP00000203852 | |
| OTTHUMP00000203853 | |
| OTTHUMP00000203855 | |
| OTTHUMP00000205983 | |
| ILK-binding protein | |
| particularly interesting new Cys-His protein 2 | |
| ILK binding protein | |
| LIM and senescent cell antigen-like domains 2 | |
| LIM and senescent cell antigen-like domains II | |
| LIMS2 | |
| PINCH II | |
| LIM and senescent cell antigen like domains 2 | |
| PINCH-2s |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 607908 |
|---|
| Mouse chromosome position | 18 |
|---|---|
| 18 B1 |
| GO ID | 0046872 |
|---|---|
| 0008270 | |
| 0030054 | |
| 0005829 | |
| 0005925 | |
| 0005634 | |
| 0005886 | |
| 0016020 | |
| 0003674 | |
| 0008150 | |
| 0005554 | |
| 0000004 |
| Rat chromosome position | 18p12 |
|---|
| Swiss-Prot Accession | B3KNZ3 |
|---|---|
| Q7Z4I7 | |
| Q53RZ1 | |
| Q7Z4I2 | |
| Q7Z4I3 | |
| Q7Z4I4 | |
| Q7Z4I5 | |
| Q9BV95 | |
| Q9H058 | |
| Q9NWG2 | |
| Q91XD2 | |
| Q5PQM7 | |
| A6NLH0 | |
| Q7Z4I6 | |
| Q7Z4I8 | |
| Q8NFE7 | |
| Q9HA13 |
| Unigene ID | Hs.469881 |
|---|---|
| Mm.24551 | |
| Rn.115282 |
| KEGG ID | hsa:55679 |
|---|---|
| mmu:225341 | |
| rno:361303 |
| Swiss-Prot ID | LIMS2_HUMAN |
|---|---|
| LIMS2_MOUSE | |
| B3KNZ3_HUMAN | |
| Q5PQM7_RAT |
| Cell Localization | Nucleus |
|---|---|
| Cell junction | |
| focal adhesion | |
| Cell membrane | |
| Plasma membrane |
| IPI ID | IPI00398576 |
|---|---|
| IPI00815737 | |
| IPI00867554 | |
| IPI00129009 | |
| IPI00364955 | |
| IPI00887698 | |
| IPI00017465 | |
| IPI00734787 |
| Homologene ID | 41214 |
|---|
| RGD ID | 1305273 |
|---|
| MGI ID | 2385067 |
|---|