| URN | urn:agi-llid:5829 |
|---|---|
| Connectivity | 487 |
| Name | Pxn |
| Description | paxillin |
| Pathway | integrin mediated signaling pathway |
|---|---|
| integrin mediated signaling pathway | |
| integrin mediated signaling pathway | |
| integrin mediated signaling pathway |
| GO Molecular Function | beta-catenin binding |
|---|---|
| protein complex binding | |
| vinculin binding | |
| integrin binding | |
| receptor signaling complex scaffold activity | |
| protein kinase binding | |
| BH4 domain binding | |
| metal ion binding | |
| zinc ion binding |
| GO Cellular Component | cell leading edge |
|---|---|
| plasma membrane | |
| lamellipodium | |
| cytoplasm | |
| microtubule associated complex | |
| cytoskeleton | |
| cell junction | |
| focal adhesion |
| GO Biological Process | cell adhesion |
|---|---|
| cellular component movement | |
| branching morphogenesis of a tube | |
| muscle contraction | |
| cytoskeleton organization | |
| signal transduction | |
| activation of MAPK activity | |
| cell-matrix adhesion | |
| peptidyl-tyrosine phosphorylation | |
| signal complex assembly | |
| cellular response to reactive oxygen species | |
| lamellipodium assembly | |
| focal adhesion assembly | |
| integrin-mediated signaling pathway |
| Ariadne Ontology | Focal junction assembly |
|---|
| Group | Focal junction assembly |
|---|---|
| cell adhesion | |
| cellular component movement | |
| branching morphogenesis of a tube | |
| muscle contraction | |
| cytoskeleton organization | |
| signal transduction | |
| activation of MAPK activity | |
| cell-matrix adhesion | |
| peptidyl-tyrosine phosphorylation | |
| signal complex assembly | |
| cellular response to reactive oxygen species | |
| lamellipodium assembly | |
| focal adhesion assembly | |
| integrin-mediated signaling pathway | |
| beta-catenin binding | |
| protein complex binding | |
| vinculin binding | |
| integrin binding | |
| receptor signaling complex scaffold activity | |
| protein kinase binding | |
| BH4 domain binding | |
| metal ion binding | |
| zinc ion binding | |
| cell leading edge | |
| plasma membrane | |
| lamellipodium | |
| cytoplasm | |
| microtubule associated complex | |
| cytoskeleton | |
| cell junction | |
| focal adhesion |
| MedScan ID | 5829 |
|---|
| Hugo ID | 9718 |
|---|
| Human chromosome position | 12q24.31 |
|---|
| LocusLink ID | 5829 |
|---|---|
| 19303 | |
| 360820 |
| Alias | FLJ16691 |
|---|---|
| hCG_1778014 | |
| paxillin | |
| Pax | |
| AW108311 | |
| AW123232 | |
| OTTMUSP00000015574 | |
| OTTMUSP00000015575 | |
| myocardial ischemic preconditioning associated protein 7 | |
| FLJ23042 | |
| hCG1778014 | |
| LOC728803 | |
| LOC732318 | |
| Pxn | |
| hypothetical protein FLJ23042 | |
| expressed sequence AW108311 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602505 |
|---|
| Mouse chromosome position | 5 60.0 cM |
|---|
| GO ID | 0008013 |
|---|---|
| 0046872 | |
| 0017166 | |
| 0008270 | |
| 0007155 | |
| 0007160 | |
| 0034614 | |
| 0006936 | |
| 0007172 | |
| 0007165 | |
| 0030054 | |
| 0005737 | |
| 0005856 | |
| 0005925 | |
| 0030027 | |
| 0005875 | |
| 0005886 | |
| 0051435 | |
| 0005178 | |
| 0032403 | |
| 0019901 | |
| 0030159 | |
| 0000187 | |
| 0048754 | |
| 0006928 | |
| 0007010 | |
| 0048041 | |
| 0007229 | |
| 0030032 | |
| 0018108 | |
| 0031252 | |
| 0005515 | |
| 0006457 |
| Rat chromosome position | 12q16 |
|---|
| Swiss-Prot Accession | P49023 |
|---|---|
| Q59GS5 | |
| Q9BTK0 | |
| Q5HYA4 | |
| Q6ZQU7 | |
| Q3UG90 | |
| Q8VI36 | |
| O88294 | |
| Q99LE7 | |
| Q66H76 | |
| Q1EG89 | |
| B2RAI3 | |
| O14970 | |
| O14971 | |
| O60360 | |
| Q3TB62 | |
| Q3TZQ6 | |
| Q8VI37 | |
| Q7Z7K5 | |
| Q96BS5 | |
| Q96FS2 | |
| Q9H5U1 |
| PIR ID | A55933 |
|---|
| Unigene ID | Hs.446336 |
|---|---|
| Mm.18714 | |
| Rn.75 |
| KEGG ID | hsa:5829 |
|---|---|
| mmu:19303 | |
| rno:360820 |
| Swiss-Prot ID | PAXI_RAT |
|---|---|
| PAXI_HUMAN | |
| PAXI_MOUSE | |
| Q9BTK0_HUMAN | |
| Q59GS5_HUMAN | |
| Q3UG90_MOUSE | |
| Q5HYA4_HUMAN |
| Cell Localization | Cytoplasm |
|---|---|
| cytoskeleton | |
| Cell junction | |
| focal adhesion | |
| Plasma membrane | |
| Nucleus |
| IPI ID | IPI00471807 |
|---|---|
| IPI00220030 | |
| IPI00220031 | |
| IPI00335634 | |
| IPI00128703 | |
| IPI00165881 | |
| IPI00335727 | |
| IPI00555917 | |
| IPI00386154 | |
| IPI00890738 | |
| IPI00794285 | |
| IPI00796494 | |
| IPI00790898 | |
| IPI00745434 | |
| IPI00376480 | |
| IPI00363651 |
| Homologene ID | 37697 |
|---|
| RGD ID | 1305759 |
|---|
| MGI ID | 108295 |
|---|
| Source | Curated |
|---|