| URN | urn:agi-llid:9706 |
|---|---|
| Connectivity | 20 |
| Name | Ulk2 |
| Description | unc-51-like kinase 2 (C. elegans) |
| Notes | This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq] |
| Pathway | autophagy pathway |
|---|
| GO Molecular Function | nucleotide binding |
|---|---|
| transferase activity | |
| ATP binding | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity |
| GO Biological Process | negative regulation of collateral sprouting |
|---|---|
| axon extension | |
| axonogenesis | |
| signal transduction | |
| protein amino acid phosphorylation |
| Group | negative regulation of collateral sprouting |
|---|---|
| axon extension | |
| axonogenesis | |
| signal transduction | |
| protein amino acid phosphorylation | |
| nucleotide binding | |
| transferase activity | |
| ATP binding | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity |
| MedScan ID | 9706 |
|---|
| Hugo ID | 13480 |
|---|
| Human chromosome position | 17p11.2 |
|---|
| LocusLink ID | 9706 |
|---|---|
| 29869 | |
| 303206 |
| Alias | ATG1B |
|---|---|
| Unc51.2 | |
| KIAA0623 | |
| serine/threonine-protein kinase ULK2 | |
| AU015340 | |
| mKIAA0623 | |
| A830085I22Rik | |
| RP23-278F12.5 | |
| OTTMUSP00000006044 | |
| unc-51-like kinase 2 | |
| serine/threonine-protein kinase Unc51.2 | |
| A830085I22 | |
| likely ortholog of mouse Unc-51 like kinase 2 | |
| OTTHUMP00000065847 | |
| Ulk2 | |
| unc-51 (C. elegans)-like kinase 2 | |
| unc-51 (C. elegans)-like kinase II | |
| Unc-51 like kinase 2 | |
| Unc-51 like kinase 2 (C. elegans) | |
| UNC-51-like kinase (ULK) 2 | |
| UNC-51-like kinase (ULK) II | |
| unc-51-like kinase II |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 608650 |
|---|
| Mouse chromosome position | 11 |
|---|
| GO ID | 0005524 |
|---|---|
| 0000166 | |
| 0004674 | |
| 0016740 | |
| 0007409 | |
| 0006468 | |
| 0007165 | |
| 0016301 | |
| 0004672 | |
| 0048675 | |
| 0048671 |
| Rat chromosome position | 10q23 |
|---|
| Swiss-Prot Accession | Q8IYT8 |
|---|---|
| Q3UG39 | |
| Q5SUB4 | |
| Q9QY01 | |
| Q3UIJ5 | |
| A8MY69 | |
| O75119 | |
| Q80TV7 | |
| Q9WTP4 |
| Unigene ID | Hs.168762 |
|---|---|
| Mm.162025 |
| KEGG ID | hsa:9706 |
|---|---|
| mmu:29869 | |
| rno:303206 |
| EC Number | 2.7.11.1 |
|---|
| Swiss-Prot ID | ULK2_HUMAN |
|---|---|
| ULK2_MOUSE | |
| Q3UG39_MOUSE | |
| Q5SUB4_MOUSE |
| IPI ID | IPI00479399 |
|---|---|
| IPI00336256 | |
| IPI00793682 | |
| IPI00200187 | |
| IPI00764501 |
| Homologene ID | 5891 |
|---|
| RGD ID | 1310181 |
|---|
| MGI ID | 1352758 |
|---|