| URN | urn:agi-llid:9047 |
|---|---|
| Connectivity | 72 |
| Name | Sh2d2a |
| Description | SH2 domain protein 2A |
| Notes | T cell-specific SH3/SH2 adaptor protein; may be a transcriptional regulator; may be a marker for T cell proliferation [RGD] |
| Pathway | vascular endothelial growth factor signaling pathway |
|---|---|
| Erk5 MAPK signaling pathway |
| GO Molecular Function | SH3-SH2 adaptor activity |
|---|---|
| SH3 domain binding |
| GO Cellular Component | membrane |
|---|---|
| soluble fraction | |
| plasma membrane | |
| cytoplasm |
| GO Biological Process | cell proliferation |
|---|---|
| multicellular organismal development | |
| cell differentiation | |
| angiogenesis | |
| signal transduction | |
| regulation of T cell activation | |
| intracellular signaling pathway |
| Group | cell proliferation |
|---|---|
| multicellular organismal development | |
| cell differentiation | |
| angiogenesis | |
| signal transduction | |
| regulation of T cell activation | |
| intracellular signaling pathway | |
| SH3-SH2 adaptor activity | |
| SH3 domain binding | |
| membrane | |
| soluble fraction | |
| plasma membrane | |
| cytoplasm |
| MedScan ID | 9047 |
|---|
| Hugo ID | 10821 |
|---|
| Human chromosome position | 1q21 |
|---|
| LocusLink ID | 9047 |
|---|---|
| 27371 | |
| 310688 |
| Alias | SCAP |
|---|---|
| TSAD | |
| VRAP | |
| F2771 | |
| RP11-66D17.12 | |
| SH2 domain-containing protein 2A | |
| SH2 domain protein 2A | |
| VEGF receptor-associated protein | |
| T cell specific adapter protein TSAd | |
| T lymphocyte specific adaptor protein | |
| Lad | |
| Ribp | |
| Rlk/Itk-binding protein | |
| Lck-associated adapter protein | |
| T cell-specific adapter protein | |
| p56Lck-associated adapter protein | |
| Lad/RIBP | |
| Lad/TSAd | |
| Lck-associated adaptor protein | |
| OTTHUMP00000038737 | |
| RIBP/Lad | |
| Rlk/Itk binding protein | |
| SH2 domain containing 2A | |
| SH2D2A | |
| T cell specific adapter protein | |
| T cell specific adaptor protein | |
| T cell-specific adaptor protein | |
| T lymphocyte specific adapter protein | |
| T-cell specific adapter protein | |
| T-cell specific adaptor protein | |
| T-cell-specific adapter protein | |
| T-cell-specific adaptor protein | |
| the T cell-specific adapter protein | |
| the T-cell-specific adapter protein | |
| TSAd/Lad | |
| T cell specific adpater protein TSAd |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604514 |
|---|
| Mouse chromosome position | 3 42.6 cM |
|---|
| GO ID | 0017124 |
|---|---|
| 0005070 | |
| 0001525 | |
| 0030154 | |
| 0007275 | |
| 0007165 | |
| 0005737 | |
| 0005625 | |
| 0008283 | |
| 0016020 | |
| 0005886 | |
| 0023034 | |
| 0050863 | |
| 0007242 | |
| 0005515 |
| Rat chromosome position | 2q34 |
|---|
| Swiss-Prot Accession | Q5UBZ2 |
|---|---|
| Q5VZS4 | |
| Q9NP31 | |
| Q5UBZ3 | |
| Q5UBZ1 | |
| Q5D0E4 | |
| Q9QXK9 | |
| Q3TA00 | |
| Q5I0Q2 | |
| Q71LH9 | |
| Q9JHP6 | |
| O43817 | |
| Q5VZS5 | |
| Q9UPA7 |
| Unigene ID | Hs.103527 |
|---|---|
| Mm.86361 | |
| Rn.9034 |
| KEGG ID | hsa:9047 |
|---|---|
| mmu:27371 | |
| rno:310688 |
| Swiss-Prot ID | SH22A_MOUSE |
|---|---|
| SH22A_HUMAN | |
| Q5UBZ3_HUMAN | |
| Q5VZS4_HUMAN | |
| Q5UBZ2_HUMAN | |
| Q5D0E4_MOUSE | |
| Q5I0Q2_RAT |
| Cell Localization | Cytoplasm |
|---|---|
| Cell membrane | |
| Plasma membrane |
| IPI ID | IPI00135104 |
|---|---|
| IPI00225758 | |
| IPI00099806 | |
| IPI00220388 | |
| IPI00936634 | |
| IPI00220389 | |
| IPI00411251 |
| Homologene ID | 2958 |
|---|
| RGD ID | 1303076 |
|---|
| MGI ID | 1351596 |
|---|
| Source | Curated |
|---|