| URN | urn:agi-llid:8829 |
|---|---|
| Connectivity | 267 |
| Name | Nrp1 |
| Description | neuropilin 1 |
| Notes | transmembrane protein that acts as a receptor for semaphorin III; may play a role in neuronal development [RGD] |
| Pathway | vascular endothelial growth factor signaling pathway |
|---|
| GO Molecular Function | growth factor binding |
|---|---|
| vascular endothelial growth factor receptor activity | |
| receptor activity | |
| semaphorin receptor activity |
| GO Cellular Component | extracellular region |
|---|---|
| membrane | |
| plasma membrane | |
| integral to membrane | |
| axon |
| GO Biological Process | cell adhesion |
|---|---|
| positive regulation of cell proliferation | |
| multicellular organismal development | |
| cell-cell signaling | |
| dendrite development | |
| organ morphogenesis | |
| patterning of blood vessels | |
| cell differentiation | |
| angiogenesis | |
| negative regulation of axon extension | |
| negative regulation of axon extension involved in axon guidance | |
| nervous system development | |
| heart development | |
| dichotomous subdivision of terminal units involved in salivary gland branching | |
| signal transduction | |
| axon guidance | |
| cell migration | |
| axonal fasciculation | |
| response to wounding | |
| vascular endothelial growth factor receptor signaling pathway |
| Ariadne Ontology | NRP |
|---|
| Group | NRP |
|---|---|
| extracellular region | |
| cell adhesion | |
| positive regulation of cell proliferation | |
| multicellular organismal development | |
| cell-cell signaling | |
| dendrite development | |
| organ morphogenesis | |
| patterning of blood vessels | |
| cell differentiation | |
| angiogenesis | |
| negative regulation of axon extension | |
| negative regulation of axon extension involved in axon guidance | |
| nervous system development | |
| heart development | |
| dichotomous subdivision of terminal units involved in salivary gland branching | |
| signal transduction | |
| axon guidance | |
| cell migration | |
| axonal fasciculation | |
| response to wounding | |
| vascular endothelial growth factor receptor signaling pathway | |
| growth factor binding | |
| vascular endothelial growth factor receptor activity | |
| receptor activity | |
| semaphorin receptor activity | |
| membrane | |
| plasma membrane | |
| integral to membrane | |
| axon |
| MedScan ID | 8829 |
|---|
| Hugo ID | 8004 |
|---|
| Human chromosome position | 10p12 |
|---|
| LocusLink ID | 8829 |
|---|---|
| 18186 | |
| 246331 |
| Alias | NP1 |
|---|---|
| NRP | |
| BDCA4 | |
| CD304 | |
| VEGF165R | |
| DKFZp781F1414 | |
| DKFZp686A03134 | |
| RP11-342D11.1 | |
| neuropilin-1 | |
| OTTHUMP00000020818 | |
| OTTHUMP00000020819 | |
| transmembrane receptor | |
| vascular endothelial cell growth factor 165 receptor | |
| NP-1 | |
| Npn1 | |
| NPN-1 | |
| C530029I03 | |
| A5 protein | |
| Neuropilin-1 precursor (A5 protein) | |
| GNB:2978560 | |
| GNB:7271465 | |
| LOC213175 | |
| neuropilin | |
| neuropilin 1 | |
| neuropilin I | |
| Norp | |
| NRP I | |
| NRP1 | |
| NRP1_HUMAN | |
| nucleolin-related protein | |
| nucleolin-related protein NRP | |
| OTTHUMP00000020820 | |
| OTTHUMP00000020821 | |
| soluble neuropilin-1 | |
| super conserved receptor expressed in brain III | |
| Vascular endothelial cell growth factor 165 receptors | |
| Vascular endothelial cell growth factor 165 receptor | |
| RIKEN cDNA 3230401K02 gene | |
| Vascular endothelial cell growth factor 165 receptors | |
| hypothetical protein C530029I03 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602069 |
|---|
| Mouse chromosome position | 8 73.0 cM |
|---|
| GO ID | 0019838 |
|---|---|
| 0004872 | |
| 0017154 | |
| 0005021 | |
| 0007411 | |
| 0007413 | |
| 0007155 | |
| 0030154 | |
| 0016477 | |
| 0007267 | |
| 0016358 | |
| 0060666 | |
| 0007507 | |
| 0007275 | |
| 0048843 | |
| 0007399 | |
| 0009887 | |
| 0001569 | |
| 0008284 | |
| 0009611 | |
| 0007165 | |
| 0030424 | |
| 0005576 | |
| 0016021 | |
| 0005886 | |
| 0001525 | |
| 0030517 | |
| 0048010 | |
| 0016020 | |
| 0005515 | |
| 0042802 | |
| 0005783 | |
| 0005624 |
| Rat chromosome position | 19q12 |
|---|
| Swiss-Prot Accession | O14786 |
|---|---|
| Q68DN3 | |
| Q96I90 | |
| Q59F20 | |
| Q6AWA9 | |
| Q5JWQ1 | |
| Q5JWQ2 | |
| Q5JWQ4 | |
| Q5JWQ5 | |
| Q5JWQ6 | |
| Q5T7F0 | |
| Q5T7F1 | |
| Q6X907 | |
| Q71SW6 | |
| Q7Z5M2 | |
| Q9H2D7 | |
| Q9H2D8 | |
| Q9H2D9 | |
| Q9H2E0 | |
| Q9H2E1 | |
| Q6PAR3 | |
| P97333 | |
| Q3UFP7 | |
| Q3UQY7 | |
| Q7TQ64 | |
| Q80X28 | |
| Q9QWJ9 | |
| Q9QX38 | |
| B0LPG9 | |
| O60461 | |
| Q5T7F2 | |
| Q5T7F3 | |
| Q96IH5 | |
| Q86T59 |
| Unigene ID | Hs.131704 |
|---|---|
| Hs.653996 | |
| Mm.271745 | |
| Rn.10815 | |
| Hs.714624 | |
| Mm.423531 | |
| Hs.707741 | |
| Mm.391997 | |
| Mm.399759 |
| KEGG ID | hsa:8829 |
|---|---|
| mmu:18186 | |
| rno:246331 |
| Swiss-Prot ID | NRP1_RAT |
|---|---|
| NRP1_HUMAN | |
| Q6AWA9_HUMAN | |
| Q6PAR3_MOUSE | |
| Q59F20_HUMAN | |
| Q96I90_HUMAN | |
| Q68DN3_HUMAN | |
| NRP1_MOUSE | |
| B0LPG9_HUMAN |
| Cell Localization | Membrane |
|---|---|
| Cell membrane | |
| Secreted | |
| Plasma membrane |
| IPI ID | IPI00212307 |
|---|---|
| IPI00299594 | |
| IPI00607733 | |
| IPI00643127 | |
| IPI00938475 | |
| IPI00749187 | |
| IPI00165438 | |
| IPI00646134 | |
| IPI00644187 | |
| IPI00643859 | |
| IPI00873301 | |
| IPI00639917 | |
| IPI00552112 | |
| IPI00123996 |
| Homologene ID | 2876 |
|---|
| RGD ID | 621588 |
|---|
| MGI ID | 106206 |
|---|