| URN | urn:agi-llid:5228 |
|---|---|
| Connectivity | 287 |
| Name | Pgf |
| Description | placental growth factor |
| Notes | forms a heterodimer with VEGF; may play a role in vascular endothelial cell proliferation [RGD] |
| Pathway | vascular endothelial growth factor signaling pathway |
|---|
| GO Molecular Function | protein homodimerization activity |
|---|---|
| growth factor activity | |
| protein heterodimerization activity | |
| vascular endothelial growth factor receptor binding | |
| heparin binding |
| GO Cellular Component | extracellular region |
|---|---|
| membrane | |
| extracellular space |
| GO Biological Process | positive regulation of cell proliferation |
|---|---|
| multicellular organismal development | |
| female pregnancy | |
| cell-cell signaling | |
| cell differentiation | |
| angiogenesis | |
| regulation of morphogenesis of a branching structure | |
| branching involved in ureteric bud morphogenesis | |
| signal transduction | |
| positive regulation of cell division | |
| positive regulation of endothelial cell proliferation | |
| cellular response to hormone stimulus | |
| response to drug | |
| response to hypoxia |
| Ariadne Ontology | GF |
|---|
| Group | GF |
|---|---|
| extracellular region | |
| positive regulation of cell proliferation | |
| multicellular organismal development | |
| female pregnancy | |
| cell-cell signaling | |
| cell differentiation | |
| angiogenesis | |
| regulation of morphogenesis of a branching structure | |
| branching involved in ureteric bud morphogenesis | |
| signal transduction | |
| positive regulation of cell division | |
| positive regulation of endothelial cell proliferation | |
| cellular response to hormone stimulus | |
| response to drug | |
| response to hypoxia | |
| protein homodimerization activity | |
| growth factor activity | |
| protein heterodimerization activity | |
| vascular endothelial growth factor receptor binding | |
| heparin binding | |
| membrane | |
| extracellular space |
| MedScan ID | 5228 |
|---|
| Hugo ID | 8893 |
|---|
| Human chromosome position | 14q24-q31 |
|---|
| LocusLink ID | 5228 |
|---|---|
| 18654 | |
| 94203 |
| Alias | PGFL |
|---|---|
| PLGF | |
| PlGF-2 | |
| D12S1900 | |
| SHGC-10760 | |
| placenta growth factor | |
| placental growth factor-like | |
| placental growth factor, vascular endothelial growth factor-related protein | |
| PIGF | |
| AI854365 | |
| MGC93298 | |
| PGF | |
| PIR:A41236 | |
| placental growth factor | |
| Placental growth factor, vascular endothelial growth factor-related | |
| PlGF II | |
| PlGF IIs | |
| PLGF_HUMAN | |
| PlGF-1/PlGF II | |
| PlGF-1/PlGF-2 | |
| Placenta growth factor precursor |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 601121 |
|---|
| Mouse chromosome position | 12 39.0 cM |
|---|
| GO ID | 0008083 |
|---|---|
| 0008201 | |
| 0046982 | |
| 0042803 | |
| 0001525 | |
| 0001658 | |
| 0030154 | |
| 0007267 | |
| 0032870 | |
| 0007565 | |
| 0007275 | |
| 0051781 | |
| 0008284 | |
| 0001938 | |
| 0060688 | |
| 0042493 | |
| 0001666 | |
| 0007165 | |
| 0005576 | |
| 0005615 | |
| 0016020 | |
| 0005172 | |
| 0005515 | |
| 0008283 | |
| 0000074 |
| Rat chromosome position | 6q31 |
|---|
| Swiss-Prot Accession | P49763 |
|---|---|
| Q53XY6 | |
| Q86TW6 | |
| P49764 | |
| Q544A5 | |
| Q63434 | |
| Q07101 | |
| Q9BV78 | |
| Q9Y6S8 |
| PIR ID | A41236 |
|---|---|
| A56125 |
| Unigene ID | Hs.252820 |
|---|---|
| Mm.4809 | |
| Rn.6960 |
| KEGG ID | hsa:5228 |
|---|---|
| mmu:18654 | |
| rno:94203 |
| Swiss-Prot ID | PLGF_HUMAN |
|---|---|
| PLGF_MOUSE | |
| PLGF_RAT | |
| Q544A5_MOUSE | |
| Q53XY6_HUMAN |
| Cell Localization | Secreted |
|---|---|
| Extracellular |
| IPI ID | IPI00028074 |
|---|---|
| IPI00219514 | |
| IPI00219515 | |
| IPI00309442 | |
| IPI00209021 | |
| IPI00384164 |
| Homologene ID | 1978 |
|---|
| RGD ID | 619850 |
|---|
| MGI ID | 105095 |
|---|