| URN | urn:agi-llid:170911 |
|---|---|
| Connectivity | 1 |
| Name | Pik3ca |
| Description | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide |
| Notes | expression of the human homolog is associated with increased cell proliferation and decreased apoptosis and may play a role in ovarian cancer progression [RGD] |
| Pathway | phosphatidylinositol 3-kinase-Akt signaling pathway |
|---|---|
| phosphatidylinositol 3-kinase-Akt signaling pathway | |
| endometrial cancer pathway | |
| non-small cell lung cancer pathway |
| GO Molecular Function | transferase activity |
|---|---|
| phosphotransferase activity, alcohol group as acceptor | |
| inositol or phosphatidylinositol kinase activity | |
| 1-phosphatidylinositol-3-kinase activity | |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
| GO Cellular Component | cytosol |
|---|---|
| phosphoinositide 3-kinase complex |
| GO Biological Process | signal transduction |
|---|---|
| phosphoinositide-mediated signaling | |
| phosphoinositide phosphorylation |
| Group | signal transduction |
|---|---|
| phosphoinositide-mediated signaling | |
| phosphoinositide phosphorylation | |
| transferase activity | |
| phosphotransferase activity, alcohol group as acceptor | |
| inositol or phosphatidylinositol kinase activity | |
| 1-phosphatidylinositol-3-kinase activity | |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | |
| cytosol | |
| phosphoinositide 3-kinase complex |
| MedScan ID | 170911 |
|---|
| LocusLink ID | 170911 |
|---|
| Alias | MGC116320 |
|---|---|
| phosphatidylinositol 3-kinase, catalytic, alpha polypeptide |
| Organism | Rattus norvegicus |
|---|
| GO ID | 0016303 |
|---|---|
| 0004428 | |
| 0046934 | |
| 0016773 | |
| 0016740 | |
| 0046854 | |
| 0048015 | |
| 0007165 | |
| 0005829 | |
| 0005942 | |
| 0005488 | |
| 0043560 | |
| 0006916 | |
| 0006006 | |
| 0043066 | |
| 0006468 | |
| 0043491 | |
| 0040014 | |
| 0005737 | |
| 0030027 | |
| 0005739 | |
| 0005515 |
| Rat chromosome position | 2q25 |
|---|
| Swiss-Prot Accession | Q91XL6 |
|---|
| Unigene ID | Rn.44193 |
|---|---|
| Rn.190480 | |
| Rn.165275 |
| KEGG ID | rno:170911 |
|---|
| IPI ID | IPI00781719 |
|---|---|
| IPI00779888 | |
| IPI00211380 | |
| IPI00769166 | |
| IPI00769069 | |
| IPI00766767 |
| RGD ID | 620916 |
|---|