| URN | urn:agi-llid:55191 |
|---|---|
| Total Entities | 0 |
| Connectivity | 13 |
| Name | Nadsyn1 |
| Description | NAD synthetase 1 |
| Notes | Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).[supplied by OMIM, Apr 2004] |
| GO Molecular Function | ligase activity |
|---|---|
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | |
| NAD+ synthase (glutamine-hydrolyzing) activity | |
| NAD+ synthase activity | |
| nucleotide binding | |
| ATP binding |
| GO Cellular Component | cytosol |
|---|
| GO Biological Process | small molecule metabolic process |
|---|---|
| NAD biosynthetic process | |
| vitamin metabolic process | |
| water-soluble vitamin metabolic process | |
| NAD metabolic process | |
| nitrogen compound metabolic process |
| Pathway | nicotinamide adenine dinucleotide biosynthetic pathway |
|---|
| Group | Glut/Gln/Pro metabolsm |
|---|---|
| NAD biosynthesis | |
| small molecule metabolic process | |
| NAD biosynthetic process | |
| vitamin metabolic process | |
| water-soluble vitamin metabolic process | |
| NAD metabolic process | |
| nitrogen compound metabolic process | |
| ligase activity | |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | |
| NAD+ synthase (glutamine-hydrolyzing) activity | |
| NAD+ synthase activity | |
| nucleotide binding | |
| ATP binding | |
| cytosol |
| LocusLink ID | 55191 |
|---|---|
| 78914 | |
| 353255 |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0005524 |
|---|---|
| 0003952 | |
| 0016810 | |
| 0009435 | |
| 0019674 | |
| 0044281 | |
| 0006766 | |
| 0006767 | |
| 0005829 | |
| 0008795 | |
| 0016874 | |
| 0000166 | |
| 0006807 |
| Alias | glutamine-dependent NAD(+) synthetase |
|---|---|
| NAD(+) synthase | |
| NAD(+) synthetase | |
| glutamine-dependent NAD synthetase | |
| 9130012B15Rik | |
| NH3-dependent NAD+ synthetase-like protein | |
| NH3-dependent NAD(+) synthetase-like protein | |
| Qns1 | |
| NH3-dependent NAD synthase-like protein | |
| NAD(+) synthetase 1 | |
| NADSYN1 | |
| NH3-dependent NAD synthetase-like protein | |
| NH3-dependent NAD+ synthase-like protein | |
| OTTMUSP00000031689 | |
| NAD(+) synthase 1 | |
| FLJ36703 | |
| NADSYN I | |
| OTTMUSP00000031693 | |
| FLJ10631 | |
| NAD synthetase I | |
| glutamine-dependent NAD synthase | |
| FLJ40627 | |
| NAD synthase 1 | |
| NAD synthase I | |
| NAD synthetase 1 | |
| 9130012B15 |
| Mouse chromosome position | 7 |
|---|
| OMIM ID | 608285 |
|---|
| Rat chromosome position | 1q41 |
|---|
| Hugo ID | 29832 |
|---|
| Human chromosome position | 11q13.4 |
|---|
| Swiss-Prot Accession | Q6IA69 |
|---|---|
| B3KUU4 | |
| Q711T7 | |
| Q812E8 | |
| Q86SN2 | |
| Q9HA25 | |
| Q9NVM8 | |
| Q711P6 | |
| Q8CFY6 | |
| Q9D280 |
| Unigene ID | Hs.556986 |
|---|---|
| Mm.35104 | |
| Rn.22886 |
| KEGG ID | hsa:55191 |
|---|---|
| mmu:78914 | |
| rno:353255 |
| Swiss-Prot ID | NADE_HUMAN |
|---|---|
| NADE_RAT | |
| NADE_MOUSE |
| EC Number | 6.3.5.1 |
|---|
| Ensembl ID | ENSG00000172890 |
|---|---|
| ENSP00000326424 | |
| ENST00000319023 | |
| ENSP00000443718 | |
| ENST00000539574 | |
| ENSMUSG00000031090 | |
| ENSMUSP00000033415 | |
| ENSMUST00000033415 | |
| ENSRNOG00000020736 | |
| ENSRNOP00000028175 | |
| ENSRNOT00000028175 |
| Homologene ID | 6098 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1926164 |
|---|
| RGD ID | 727801 |
|---|
| MedScan ID | 55191 |
|---|