| URN | urn:agi-llid:681891 |
|---|---|
| Connectivity | 3 |
| Name | Oaz3 |
| Description | ornithine decarboxylase antizyme 3 |
| Notes | Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of antizyme 3, encoded by this gene, is restricted to testis germ cells. [provided by RefSeq] |
| Pathway | New Pathway (6) |
|---|---|
| polyamine metabolic pathway |
| GO Molecular Function | ornithine decarboxylase inhibitor activity |
|---|
| GO Cellular Component | cytoplasm |
|---|---|
| nucleus |
| Group | ornithine decarboxylase inhibitor activity |
|---|---|
| cytoplasm | |
| nucleus |
| MedScan ID | 612477 |
|---|
| LocusLink ID | 689588 |
|---|---|
| 681891 |
| Alias | Az3 |
|---|---|
| Oaz-t | |
| ornithine decarboxylase antizyme 3 | |
| antizyme 3 | |
| LOC681891 |
| Organism | Rattus norvegicus |
|---|
| GenBank ID | NC_005101 |
|---|---|
| NM_001101018 | |
| NW_001084807 | |
| NW_047626 | |
| AC_000070 | |
| AC133978 | |
| AW529628 | |
| DQ431008 | |
| ABF59049 |
| GO ID | 0008073 |
|---|---|
| 0005737 | |
| 0005634 |
| Rat chromosome position | 2q34 |
|---|
| Swiss-Prot Accession | A1BPI0 |
|---|
| Unigene ID | Rn.43319 |
|---|
| KEGG ID | rno:689588 |
|---|
| Swiss-Prot ID | A1BPI0_RAT |
|---|
| IPI ID | IPI00204807 |
|---|
| RGD ID | 1599278 |
|---|