| URN | urn:agi-llid:54498 |
|---|---|
| Connectivity | 53 |
| Name | Smox |
| Description | spermine oxidase |
| Notes | The product of this gene is the polyamine oxidase. This enzyme potentially represents a new class of catabolic enzymes in the mammalian polyamine metabolic pathway capable of the efficient oxidation of polyamines. More than five transcript variants encoding four active isoenzymes have been identified for this gene, however, not all variants have been fully described. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq] |
| Pathway | New Pathway (6) |
|---|---|
| polyamine metabolic pathway |
| GO Molecular Function | oxidoreductase activity |
|---|---|
| oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor | |
| polyamine oxidase activity |
| GO Cellular Component | cytoplasm |
|---|---|
| nucleus |
| GO Biological Process | oxidation reduction |
|---|---|
| spermine catabolic process |
| Group | oxidation reduction |
|---|---|
| spermine catabolic process | |
| oxidoreductase activity | |
| oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor | |
| polyamine oxidase activity | |
| cytoplasm | |
| nucleus |
| MedScan ID | 54498 |
|---|
| Hugo ID | 15862 |
|---|
| Human chromosome position | 20p13 |
|---|
| LocusLink ID | 54498 |
|---|---|
| 228608 | |
| 308652 |
| Alias | PAO |
|---|---|
| SMO | |
| PAOH1 | |
| MGC1010 | |
| C20orf16 | |
| FLJ20746 | |
| RP4-779E11.4 | |
| spermine oxidase | |
| PAO-1 | |
| OTTHUMP00000030156 | |
| polyamine oxidase 1 | |
| flavin containing amine oxidase | |
| flavin-containing spermine oxidase | |
| putative cyclin G1 interacting protein | |
| B130066H01Rik | |
| RP23-442K11.1 | |
| OTTMUSP00000017325 | |
| OTTMUSP00000017331 | |
| OTTMUSP00000017332 | |
| OTTMUSP00000017333 | |
| B130066H01 | |
| chromosome 20 open reading frame 16 | |
| dJ779E11 | |
| dJ779E11.1 | |
| OTTHUMP00000030155 | |
| OTTHUMP00000030157 | |
| OTTHUMP00000030158 | |
| PAOh I | |
| polyamine oxidase | |
| polyamine oxidase I | |
| Smox |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| Mouse chromosome position | 2 |
|---|
| GO ID | 0016491 |
|---|---|
| 0055114 | |
| 0005737 | |
| 0046592 | |
| 0046208 | |
| 0005634 | |
| 0016647 |
| Rat chromosome position | 3q36 |
|---|
| Swiss-Prot Accession | Q9NWM0 |
|---|---|
| Q5TE25 | |
| Q3UPW5 | |
| Q99K82 | |
| Q3TLR8 | |
| B1WBU6 | |
| A2ANQ8 | |
| A2ANQ9 | |
| A2ANR0 | |
| A2ANR1 | |
| A2ANR2 | |
| Q70LA3 | |
| Q70LA4 | |
| Q70LA5 | |
| Q70LA7 | |
| Q70LA8 | |
| Q70LA9 | |
| Q70LB0 | |
| Q8CJ56 | |
| Q8CJ57 | |
| A2A2P5 | |
| A2A2P6 | |
| Q5TE26 | |
| Q5TE27 | |
| Q6UY28 | |
| Q8IX00 | |
| Q96LC3 | |
| Q96LC4 | |
| Q96QT3 | |
| Q9BW38 | |
| Q9H6H1 | |
| Q9NP51 | |
| Q9NPY1 | |
| Q9NPY2 | |
| D3DVZ4 |
| PIR ID | T47142 |
|---|
| Unigene ID | Hs.433337 |
|---|---|
| Mm.136586 | |
| Rn.100278 |
| KEGG ID | hsa:54498 |
|---|---|
| mmu:228608 | |
| rno:308652 |
| EC Number | 1.5.3.- |
|---|---|
| 1.5.3.16 |
| Swiss-Prot ID | SMOX_MOUSE |
|---|---|
| SMOX_HUMAN | |
| B1WBU6_RAT | |
| D3DVZ4_HUMAN | |
| Q3UPW5_MOUSE | |
| A2A2P5_HUMAN | |
| A2A2P6_HUMAN |
| Cell Localization | Cytoplasm |
|---|---|
| Nucleus |
| IPI ID | IPI00115612 |
|---|---|
| IPI00407774 | |
| IPI00453549 | |
| IPI00453550 | |
| IPI00453552 | |
| IPI00453553 | |
| IPI00453554 | |
| IPI00453556 | |
| IPI00453648 | |
| IPI00828527 | |
| IPI00424178 | |
| IPI00424179 | |
| IPI00424181 | |
| IPI00424182 | |
| IPI00424183 | |
| IPI00561778 | |
| IPI00876446 | |
| IPI00749570 | |
| IPI00453551 | |
| IPI00758232 | |
| IPI00390620 | |
| IPI00393941 | |
| IPI00557247 | |
| IPI00568604 | |
| IPI00210213 |
| Homologene ID | 69268 |
|---|
| RGD ID | 1306049 |
|---|
| MGI ID | 2445356 |
|---|