| URN | urn:agi-llid:3516 |
|---|---|
| Connectivity | 166 |
| Name | Rbpj |
| Description | recombining binding protein suppressor of hairless (Drosophila) |
| Pathway | Notch -> RBPJ/HES/HEY signaling |
|---|---|
| Notch signaling pathway |
| GO Molecular Function | transcription regulator activity |
|---|---|
| chromatin binding | |
| recombinase activity | |
| transcription activator activity | |
| transcription factor activity | |
| protein N-terminus binding | |
| transcription factor binding | |
| protein complex binding | |
| DNA binding | |
| sequence-specific DNA binding |
| GO Cellular Component | protein complex |
|---|---|
| protein-DNA complex | |
| nucleolus | |
| transcription factor complex | |
| nucleus |
| GO Biological Process | negative regulation of cell proliferation |
|---|---|
| positive regulation of cell proliferation | |
| defense response to bacterium | |
| negative regulation of cell differentiation | |
| cell fate commitment | |
| angiogenesis | |
| heart development | |
| hemopoiesis | |
| pituitary gland development | |
| sebaceous gland development | |
| epidermal cell fate specification | |
| neuron differentiation | |
| epithelial to mesenchymal transition | |
| regulation of timing of cell differentiation | |
| keratinocyte differentiation | |
| B cell differentiation | |
| hair follicle maturation | |
| neuron projection development | |
| negative regulation of transcription, DNA-dependent | |
| positive regulation of transcription | |
| regulation of transcription, DNA-dependent | |
| regulation of transcription from RNA polymerase II promoter | |
| positive regulation of smooth muscle cell proliferation | |
| negative regulation of smooth muscle cell migration | |
| negative regulation of smooth muscle cell apoptosis | |
| transcription | |
| DNA recombination | |
| regulation of gene expression | |
| Notch signaling pathway |
| Ariadne Ontology | DNA recombination |
|---|---|
| Nucleolus organization and biogenesis | |
| RBPJ |
| Group | DNA recombination |
|---|---|
| Nucleolus organization and biogenesis | |
| RBPJ | |
| transcription regulator activity | |
| negative regulation of cell proliferation | |
| positive regulation of cell proliferation | |
| defense response to bacterium | |
| negative regulation of cell differentiation | |
| cell fate commitment | |
| angiogenesis | |
| heart development | |
| hemopoiesis | |
| pituitary gland development | |
| sebaceous gland development | |
| epidermal cell fate specification | |
| neuron differentiation | |
| epithelial to mesenchymal transition | |
| regulation of timing of cell differentiation | |
| keratinocyte differentiation | |
| B cell differentiation | |
| hair follicle maturation | |
| neuron projection development | |
| negative regulation of transcription, DNA-dependent | |
| positive regulation of transcription | |
| regulation of transcription, DNA-dependent | |
| regulation of transcription from RNA polymerase II promoter | |
| positive regulation of smooth muscle cell proliferation | |
| negative regulation of smooth muscle cell migration | |
| negative regulation of smooth muscle cell apoptosis | |
| transcription | |
| DNA recombination | |
| regulation of gene expression | |
| Notch signaling pathway | |
| chromatin binding | |
| recombinase activity | |
| transcription activator activity | |
| transcription factor activity | |
| protein N-terminus binding | |
| transcription factor binding | |
| protein complex binding | |
| DNA binding | |
| sequence-specific DNA binding | |
| protein complex | |
| protein-DNA complex | |
| nucleolus | |
| transcription factor complex | |
| nucleus |
| MedScan ID | 3516 |
|---|
| Hugo ID | 5724 |
|---|
| Human chromosome position | 4p15.2 |
|---|
| LocusLink ID | 3516 |
|---|---|
| 19664 |
| Alias | SUH |
|---|---|
| csl | |
| CBF1 | |
| KBF2 | |
| RBP-J | |
| RBPJK | |
| IGKJRB | |
| RBPSUH | |
| IGKJRB1 | |
| MGC61669 | |
| recombining binding protein suppressor of hairless | |
| CBF-1 | |
| RBP-JK | |
| RBP-J kappa | |
| OTTHUMP00000123441 | |
| H-2K binding factor-2 | |
| suppressor of hairless homolog | |
| renal carcinoma antigen NY-REN-30 | |
| j kappa-recombination signal-binding protein | |
| immunoglobulin kappa J region recombination signal binding protein 1 | |
| Igkrsbp | |
| AI843960 | |
| ENSMUSG00000067298 | |
| CBF I | |
| IGKJRB I | |
| Igkrsbps | |
| immunoglobulin kappa J region recombination signal binding protein I | |
| J kappa-recombination signal binding protein | |
| J-kappa recombination sequence-binding protein | |
| Lag-1 | |
| OTTHUMP00000123440 | |
| recombination signal binding protein for immunoglobulin kappa J region | |
| suppressor of hairless |
| Organism | Homo sapiens |
|---|---|
| Mus musculus |
| OMIM ID | 147183 |
|---|
| Mouse chromosome position | 5 37.5 cM |
|---|
| GO ID | 0003677 |
|---|---|
| 0032403 | |
| 0000150 | |
| 0003700 | |
| 0006310 | |
| 0007219 | |
| 0034392 | |
| 0014912 | |
| 0045892 | |
| 0031175 | |
| 0048661 | |
| 0045941 | |
| 0005730 | |
| 0005634 | |
| 0043234 | |
| 0032993 | |
| 0003682 | |
| 0047485 | |
| 0043565 | |
| 0016563 | |
| 0008134 | |
| 0030528 | |
| 0030183 | |
| 0001525 | |
| 0045165 | |
| 0042742 | |
| 0009957 | |
| 0001837 | |
| 0048820 | |
| 0007507 | |
| 0030097 | |
| 0030216 | |
| 0045596 | |
| 0008285 | |
| 0030182 | |
| 0021983 | |
| 0008284 | |
| 0010468 | |
| 0048505 | |
| 0006357 | |
| 0048733 | |
| 0005667 | |
| 0006350 | |
| 0006355 | |
| 0005515 | |
| 0045449 | |
| 0003702 | |
| 0006366 |
| Swiss-Prot Accession | Q06330 |
|---|---|
| B4DY22 | |
| Q14663 | |
| P31266 | |
| Q3UM17 | |
| Q6R5E9 | |
| Q3U6F1 | |
| Q5XKH9 | |
| Q6P1N3 | |
| Q80UN8 | |
| Q8C4Z3 | |
| Q6ZTP8 |
| PIR ID | A47214 |
|---|---|
| A42267 | |
| A43567 |
| Unigene ID | Hs.479396 |
|---|---|
| Mm.209292 | |
| Mm.427686 | |
| Mm.321004 |
| KEGG ID | hsa:3516 |
|---|---|
| mmu:19664 |
| Swiss-Prot ID | SUH_HUMAN |
|---|---|
| SUH_MOUSE | |
| Q3UM17_MOUSE | |
| B4DY22_HUMAN | |
| Q6R5E9_MOUSE |
| Cell Localization | Nucleus |
|---|
| IPI ID | IPI00030177 |
|---|---|
| IPI00218576 | |
| IPI00218578 | |
| IPI00402156 | |
| IPI00419892 | |
| IPI00807402 | |
| IPI00132267 | |
| IPI00353533 | |
| IPI00479716 | |
| IPI00460794 | |
| IPI00332627 | |
| IPI00875375 | |
| IPI00828780 |
| Homologene ID | 7511 |
|---|
| RGD ID | 1593096 |
|---|
| MGI ID | 96522 |
|---|