Protein Tp53bp1

URN	urn:agi-llid:7158
Total Entities	0
Connectivity	234
Name	Tp53bp1
Description	tumor protein p53 binding protein 1

Ariadne Ontology	Transcription factors

GO Molecular Function	p53 binding
	transcription factor binding
	RNA polymerase II activating transcription factor binding
	methylated histone residue binding
	DNA binding
	damaged DNA binding
	telomeric DNA binding
	RNA polymerase II transcription cofactor activity

GO Cellular Component	nucleoplasm
	chromosome, centromeric region
	kinetochore
	chromosome, telomeric region
	replication fork
	condensed chromosome kinetochore
	cytoplasm
	chromosome
	nucleus

GO Biological Process	positive regulation of transcription, DNA-dependent
	positive regulation of transcription from RNA polymerase II promoter
	regulation of transcription, DNA-dependent
	positive regulation of sequence-specific DNA binding transcription factor activity
	transcription, DNA-dependent
	DNA repair
	double-strand break repair
	double-strand break repair via homologous recombination
	response to DNA damage stimulus

Pathway	Double Strand DNA Non-Homologous Repair
	ataxia telangiectasia-mutated (ATM) signaling pathway
	non-homologous end joining pathway of double-strand break repair

Group	Transcription factors
	positive regulation of transcription, DNA-dependent
	positive regulation of transcription from RNA polymerase II promoter
	regulation of transcription, DNA-dependent
	positive regulation of sequence-specific DNA binding transcription factor activity
	transcription, DNA-dependent
	DNA repair
	double-strand break repair
	double-strand break repair via homologous recombination
	response to DNA damage stimulus
	p53 binding
	transcription factor binding
	RNA polymerase II activating transcription factor binding
	methylated histone residue binding
	DNA binding
	damaged DNA binding
	telomeric DNA binding
	RNA polymerase II transcription cofactor activity
	nucleoplasm
	chromosome, centromeric region
	kinetochore
	chromosome, telomeric region
	replication fork
	condensed chromosome kinetochore
	cytoplasm
	chromosome
	nucleus

MedScan ID	7158

Hugo ID	11999

Human chromosome position	15q15-q21

Alias	p202
	53BP1
	tumor suppressor p53-binding protein 1
	p53BP1
	p53-binding protein 1
	tumor protein 53-binding protein, 1
	tumor protein p53-binding protein, 1
	m53BP1
	Tp53bp1
	RP23-437L13.2
	murine p53-binding protein
	transformation related protein 53 binding-protein 1
	Trp53bp1
	transformation related protein 53 binding protein 1
	m53BP I
	tumor p53 binding
	tumor protein 53-binding protein, I
	tumor protein p53 binding protein 1
	tumor protein p53 binding protein, I
	tumor 53-binding
	Tumor suppressor p53-binding protein I
	tumour 53-binding
	tumour p53 binding
	tumour protein 53-binding protein, 1
	tumour protein 53-binding protein, I
	tumour protein p53 binding protein 1
	tumour protein p53 binding protein, I
	tumour suppressor p53-binding protein I
	Trp53bp I
	tumour suppressor p53-binding protein 1
	LOC688035
	transformation related protein 53 binding protein I
	MGC100303
	FLJ41424
	53BP I
	MGC138366
	OTTMUSP00000017048
	P531_HUMAN
	p53-binding protein I
	TP53BP I
	OTTMUSP00000017066

OMIM ID	605230

KEGG ID	hsa:7158
	mmu:27223

PIR ID	I38604

Swiss-Prot ID	TP53B_HUMAN
	TP53B_MOUSE

Mouse chromosome position	2

Rat chromosome position	3q35

Homologene ID	4137

MGI ID	1351320

RGD ID	1308039

Primary Cell Localization	Nucleus