Protein Wif1

URN urn:agi-llid:11197
Total Entities 0
Connectivity 108
Name Wif1
Description Wnt inhibitory factor 1
Notes human homolog has decreased mRNA expression in some prostate cancers and other cancers; may act as a secreted inhibitor of the Wnt signaling pathway [RGD]

Ariadne Ontology Secreted proteins

GO Molecular Function Wnt-protein binding

GO Cellular Component extracellular region

GO Biological Process negative regulation of Wnt receptor signaling pathway
signal transduction
Wnt receptor signaling pathway
positive regulation of fat cell differentiation
multicellular organismal development

Pathway Wnt signaling, canonical pathway
altered Wnt signaling, canonical pathway
canonical Wnt signaling pathway
Wnt signaling, canonical pathway

Group negative regulation of Wnt receptor signaling pathway
signal transduction
Wnt receptor signaling pathway
positive regulation of fat cell differentiation
multicellular organismal development
Wnt-protein binding
extracellular region
Secreted proteins

MedScan ID 11197

Hugo ID 18081

Human chromosome position 12q14.3

GenBank ID NC_000012
NM_007191
NP_009122
NC_018923
AC_000144
AC026124
AC135895
CH471054
EAW97146
EAW97147
AF122922
AAD25402
AK301818
BAG63265
AL711431
AY358344
AAQ88710
BC018037
AAH18037
BX647427
DB560069
DC315426
Q9Y5W5
DQ892394
ABM83320
DQ895609
ABM86535
NC_000076
NM_011915
NP_036045
AC_000032
AC140381
CH466578
EDL24411
AF122923
AAD25403
AK077698
AK142443
BAE25067
AK158359
BAE34471
AK196449
AK202617
AK207348
BC004048
AAH04048
BC013268
AAH13268
Q9WUA1
NC_005106
NM_053738
NP_446190
AC_000075
CH473960
EDM16555
EDM16556
AY030278
AAK51134
BC072473
AAH72473
Q6IN38
NT_029419
NW_001838060
NW_925395
AC_000055
NT_039500
NW_001030422
Q3TYU1
Q99KR2
NW_047776
NW_001084856
NW_000033
XM_983301
XP_988395
XM_983264
XP_988358
XM_983228
XP_988322

LocusLink ID 11197
24117
114557

Alias WIF-1
UNQ191/PRO217
wnt inhibitory factor 1
AW107799
WIF I
WIF1
WNT inhibitory factor I

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 605186

Unigene ID Hs.284122
Mm.32831
Rn.74256

KEGG ID hsa:11197
mmu:24117
rno:114557

Swiss-Prot Accession Q9Y5W5
Q3TYU1
Q9WUA1
Q6IN38
Q924Y6
Q6UXI1
Q8WVG4
Q99KR2

GO ID 0016055
0007275
0045600
0007165
0005576
0017147
0030178
0004713
0003674
0008150
0005575
0007267
0005615
0016021
0016020

PIR ID A59180

Swiss-Prot ID WIF1_MOUSE
WIF1_RAT
WIF1_HUMAN
Q3TYU1_MOUSE

Cell Localization Secreted
Extracellular

IPI ID IPI00124441
IPI00205190
IPI00554094
IPI00001863
IPI00462278

Mouse chromosome position 10
10 D2

Rat chromosome position 7q22

Homologene ID 31430

MGI ID 1344332

RGD ID 619774