| URN | urn:agi-llid:1724 |
|---|---|
| Total Entities | 0 |
| Connectivity | 39 |
| Name | Porcn |
| Description | porcupine homolog (Drosophila) |
| Notes | This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the Porc family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq] |
| Ariadne Ontology | Secreted proteins |
|---|
| GO Molecular Function | transferase activity |
|---|---|
| transferase activity, transferring acyl groups |
| GO Cellular Component | membrane |
|---|---|
| integral to endoplasmic reticulum membrane | |
| integral to membrane | |
| endoplasmic reticulum |
| GO Biological Process | Wnt receptor signaling pathway |
|---|---|
| glycoprotein metabolic process |
| Pathway | Wnt signaling, canonical pathway |
|---|---|
| altered Wnt signaling, canonical pathway | |
| Wnt signaling, canonical pathway |
| Group | Wnt receptor signaling pathway |
|---|---|
| glycoprotein metabolic process | |
| transferase activity | |
| transferase activity, transferring acyl groups | |
| membrane | |
| integral to endoplasmic reticulum membrane | |
| integral to membrane | |
| endoplasmic reticulum | |
| Secreted proteins |
| MedScan ID | 1724 |
|---|
| Hugo ID | 17652 |
|---|
| Human chromosome position | Xp11.23 |
|---|
| LocusLink ID | 1724 |
|---|---|
| 64840 | |
| 53627 | |
| 317368 |
| Alias | PPN |
|---|---|
| por | |
| DHOF | |
| FODH | |
| MG61 | |
| PORC | |
| protein-cysteine N-palmitoyltransferase porcupine | |
| 2410004O13Rik | |
| probable protein-cysteine N-palmitoyltransferase porcupine | |
| Mporc | |
| mMg61 | |
| Mporc-a | |
| Mporc-b | |
| Mporc-c | |
| Mporc-d | |
| AW045557 | |
| DXHXS7465e | |
| RP23-27I6.11-005 | |
| porcupine-A | |
| porcupine-B | |
| porcupine-C | |
| porcupine-D | |
| RGD1564947 | |
| porcupine homolog | |
| PORCN | |
| OTTMUSP00000019664 | |
| OTTMUSP00000019662 | |
| OTTHUMP00000025785 | |
| OTTHUMP00000025784 | |
| omicron-acyltransferase porcupine | |
| Porcupine | |
| Mporc-ds | |
| porcupine homolog (Drosophila) | |
| Mporc-cs | |
| OTTMUSP00000019661 | |
| RP23-27I6.11 | |
| MG(61) | |
| OTTMUSP00000019663 | |
| 2410004O13Rik(2) | |
| DNA segment, Chr X, human S7465E, expressed | |
| focal dermal hypoplasia locus | |
| likely ortholog of mouse porcupine homolog | |
| MG-61 | |
| MGC29687 | |
| 2410004O13 | |
| Mporc-as | |
| Mporc-bs | |
| dermal hypoplasia, focal |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 300651 |
|---|---|
| 305600 |
| Unigene ID | Hs.386453 |
|---|---|
| Mm.443425 | |
| Rn.63525 |
| KEGG ID | hsa:64840 |
|---|---|
| mmu:53627 | |
| rno:317368 |
| Swiss-Prot Accession | Q9H237 |
|---|---|
| Q9JJJ7 | |
| A2AC31 | |
| D4A745 | |
| B2RBN8 | |
| Q14829 | |
| Q9H234 | |
| Q9H235 | |
| Q9H236 | |
| Q9UJU7 | |
| A2AC30 | |
| A2AC32 | |
| A2AC33 | |
| Q9CWT0 | |
| Q9JJJ8 | |
| Q9JJJ9 | |
| Q9JJK0 | |
| B3KQ96 | |
| B7ZAR3 | |
| Q05CC9 |
| EC Number | 2.3.1.- |
|---|
| GO ID | 0016746 |
|---|---|
| 0016055 | |
| 0009100 | |
| 0030176 | |
| 0016740 | |
| 0005783 | |
| 0016021 | |
| 0016020 | |
| 0008415 | |
| 0005789 |
| Swiss-Prot ID | PORCN_HUMAN |
|---|---|
| PORCN_MOUSE | |
| B3KQ96_HUMAN | |
| B7ZAR3_HUMAN | |
| A2AC31_MOUSE | |
| B2RBN8_HUMAN | |
| A2AC30_MOUSE | |
| A2AC32_MOUSE | |
| A2AC33_MOUSE |
| Cell Localization | Endoplasmic reticulum membrane |
|---|
| IPI ID | IPI00010194 |
|---|---|
| IPI00183971 | |
| IPI00383252 | |
| IPI00409706 | |
| IPI00121914 | |
| IPI00162937 | |
| IPI00162939 | |
| IPI00162988 | |
| IPI00655226 | |
| IPI00409620 | |
| IPI00808407 | |
| IPI00777950 | |
| IPI00208977 | |
| IPI00208959 | |
| IPI00564742 | |
| IPI00558604 |
| Mouse chromosome position | X 2.15 cM |
|---|
| Rat chromosome position | Xq13 |
|---|
| Homologene ID | 41529 |
|---|
| MGI ID | 1890212 |
|---|
| RGD ID | 1564947 |
|---|