| URN | urn:agi-llid:166336 |
|---|---|
| Total Entities | 0 |
| Connectivity | 28 |
| Name | Prickle2 |
| Description | prickle homolog 2 (Drosophila) |
| Notes | This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011] |
| GO Molecular Function | metal ion binding |
|---|---|
| zinc ion binding |
| GO Cellular Component | membrane |
|---|---|
| nuclear membrane | |
| lateral plasma membrane | |
| apicolateral plasma membrane | |
| cytoplasm | |
| nucleus |
| GO Biological Process | establishment or maintenance of epithelial cell apical-basal polarity |
|---|---|
| neuron projection development |
| Pathway | the planar cell polarity Wnt signaling pathway |
|---|---|
| Wnt signaling, the planar cell polarity pathway |
| Group | establishment or maintenance of epithelial cell apical-basal polarity |
|---|---|
| neuron projection development | |
| metal ion binding | |
| zinc ion binding | |
| membrane | |
| nuclear membrane | |
| lateral plasma membrane | |
| apicolateral plasma membrane | |
| cytoplasm | |
| nucleus |
| MedScan ID | 166336 |
|---|
| Hugo ID | 20340 |
|---|
| Human chromosome position | 3p14.1 |
|---|
| LocusLink ID | 166336 |
|---|---|
| 243548 | |
| 312563 |
| Alias | EPM5 |
|---|---|
| prickle-like protein 2 | |
| mpk2 | |
| 6230400G14Rik | |
| 6720451F06Rik | |
| prickle-like 2 | |
| DKFZp686H1748 | |
| 6230400G14 | |
| prickle-like 2 (Drosophila) | |
| PRICKLE2 | |
| prickle homolog 2 (Drosophila) | |
| DKFZp686M031 | |
| prickle-like II | |
| DKFZp686D143 | |
| 6720451F06 | |
| LIM-only protein 6 (Triple LIM domain protein 6) | |
| prickle homolog 2 | |
| RIKEN cDNA 6230400G14 gene | |
| RIKEN cDNA 6720451F06 gene |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 608501 |
|---|---|
| 613832 |
| Unigene ID | Hs.148105 |
|---|---|
| Mm.248820 | |
| Rn.85011 | |
| Hs.699317 |
| KEGG ID | hsa:166336 |
|---|---|
| mmu:243548 | |
| rno:312563 |
| Swiss-Prot Accession | Q7Z3G6 |
|---|---|
| A7YQ68 | |
| Q80Y24 | |
| A6H652 | |
| Q0VF44 |
| GO ID | 0008270 |
|---|---|
| 0045197 | |
| 0031175 | |
| 0016327 | |
| 0005737 | |
| 0016328 | |
| 0031965 | |
| 0046872 | |
| 0016020 | |
| 0005634 |
| Swiss-Prot ID | PRIC2_MOUSE |
|---|---|
| PRIC2_HUMAN | |
| A6H652_MOUSE | |
| A7YQ68_MOUSE |
| Cell Localization | Nucleus membrane |
|---|
| IPI ID | IPI00876463 |
|---|---|
| IPI00085314 | |
| IPI00349970 | |
| IPI00795985 | |
| IPI00365177 |
| Mouse chromosome position | 6 |
|---|---|
| 6 D1 |
| Rat chromosome position | 4q34 |
|---|
| Homologene ID | 17889 |
|---|
| MGI ID | 1925144 |
|---|
| RGD ID | 1306723 |
|---|