| URN | urn:agi-llid:57216 |
|---|---|
| Total Entities | 0 |
| Connectivity | 113 |
| Name | Vangl2 |
| Description | vang-like 2 (van gogh, Drosophila) (predicted) |
| Notes | The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM] |
| Ariadne Ontology | Secreted proteins |
|---|
| GO Cellular Component | membrane |
|---|---|
| lateral plasma membrane | |
| basolateral plasma membrane | |
| apical plasma membrane | |
| integral to membrane | |
| plasma membrane | |
| cell pole | |
| cell-cell junction |
| GO Biological Process | positive regulation of JUN kinase activity |
|---|---|
| Rho protein signal transduction | |
| non-canonical Wnt receptor signaling pathway | |
| Wnt receptor signaling pathway, planar cell polarity pathway | |
| planar cell polarity pathway involved in neural tube closure | |
| planar cell polarity pathway involved in axis elongation | |
| somatic stem cell maintenance | |
| regulation of actin cytoskeleton organization | |
| epicardial cell to mesenchymal cell transition | |
| inner ear receptor cell development | |
| cardiac vascular smooth muscle cell differentiation | |
| somatic stem cell division | |
| cell migration involved in kidney development | |
| establishment of epithelial cell polarity | |
| establishment or maintenance of epithelial cell apical-basal polarity | |
| nonmotile primary cilium assembly | |
| inner ear receptor stereocilium organization | |
| wound healing | |
| regulation of establishment of planar polarity | |
| multicellular organismal development | |
| convergent extension involved in axis elongation | |
| convergent extension involved in neural plate elongation | |
| heart looping | |
| membranous septum morphogenesis | |
| establishment of planar polarity | |
| muscular septum morphogenesis | |
| cochlea morphogenesis | |
| patterning of blood vessels | |
| establishment of planar polarity involved in neural tube closure | |
| establishment of body hair planar orientation | |
| outflow tract septum morphogenesis | |
| neural tube closure | |
| orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis | |
| planar dichotomous subdivision of terminal units involved in lung branching morphogenesis | |
| lateral sprouting involved in lung morphogenesis | |
| hair follicle development | |
| anterior-posterior pattern specification | |
| digestive tract morphogenesis | |
| convergent extension involved in organogenesis | |
| apical protein localization |
| Pathway | the planar cell polarity Wnt signaling pathway |
|---|---|
| Wnt signaling, the planar cell polarity pathway |
| Group | positive regulation of JUN kinase activity |
|---|---|
| Rho protein signal transduction | |
| non-canonical Wnt receptor signaling pathway | |
| Wnt receptor signaling pathway, planar cell polarity pathway | |
| planar cell polarity pathway involved in neural tube closure | |
| planar cell polarity pathway involved in axis elongation | |
| somatic stem cell maintenance | |
| regulation of actin cytoskeleton organization | |
| epicardial cell to mesenchymal cell transition | |
| inner ear receptor cell development | |
| cardiac vascular smooth muscle cell differentiation | |
| somatic stem cell division | |
| cell migration involved in kidney development | |
| establishment of epithelial cell polarity | |
| establishment or maintenance of epithelial cell apical-basal polarity | |
| nonmotile primary cilium assembly | |
| inner ear receptor stereocilium organization | |
| wound healing | |
| regulation of establishment of planar polarity | |
| multicellular organismal development | |
| convergent extension involved in axis elongation | |
| convergent extension involved in neural plate elongation | |
| heart looping | |
| membranous septum morphogenesis | |
| establishment of planar polarity | |
| muscular septum morphogenesis | |
| cochlea morphogenesis | |
| patterning of blood vessels | |
| establishment of planar polarity involved in neural tube closure | |
| establishment of body hair planar orientation | |
| outflow tract septum morphogenesis | |
| neural tube closure | |
| orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis | |
| planar dichotomous subdivision of terminal units involved in lung branching morphogenesis | |
| lateral sprouting involved in lung morphogenesis | |
| hair follicle development | |
| anterior-posterior pattern specification | |
| digestive tract morphogenesis | |
| convergent extension involved in organogenesis | |
| apical protein localization | |
| membrane | |
| lateral plasma membrane | |
| basolateral plasma membrane | |
| apical plasma membrane | |
| integral to membrane | |
| plasma membrane | |
| cell pole | |
| cell-cell junction | |
| Secreted proteins |
| Source | Curated |
|---|---|
| GO component |
| MedScan ID | 57216 |
|---|
| Hugo ID | 15511 |
|---|
| Human chromosome position | 1q22-q23 |
|---|
| LocusLink ID | 57216 |
|---|---|
| 93840 | |
| 289229 | |
| 16951 | |
| 77606 | |
| 109293 | |
| 520544 | |
| 245949 |
| Alias | LPP1 |
|---|---|
| LTAP | |
| STB1 | |
| STBM | |
| STBM1 | |
| vang-like protein 2 | |
| strabismus 1 | |
| van Gogh-like protein 2 | |
| loop-tail protein 1 homolog | |
| loop-tail-associated protein | |
| Lp | |
| ska17 | |
| Vang1l2 | |
| loop-tail | |
| strabismus | |
| ska<m17Jus> | |
| C530001F03Rik | |
| loop-tail protein 1 | |
| vang (van gogh)-like 2 | |
| loop tail associated protein | |
| vang (van gogh, Drosophila)-like | |
| vang (van gogh)-like II | |
| van gogh-like 2 | |
| vang (van gogh, Drosophila)-like 2 | |
| strabismus gene | |
| strabismus (van gogh) homolog | |
| strabismus homolog | |
| vang (van gogh, drosophila)-like 2, vang, van gogh-like 2 | |
| vang (van gogh, Drosophila)-like II | |
| vang, van gogh-like 2 (Drosophila) | |
| vang-like 2 | |
| vang-like 2 (van gogh) | |
| vang-like 2 (van gogh, Drosophila) | |
| vang-like II | |
| vang (van gogh, drosophila)-like 2, vang, van gogh-like II | |
| VANGL2 | |
| C530001F03 | |
| KIAA1215 | |
| loop tail mutation | |
| loop-tail associated protein | |
| MGC119403 | |
| MGC119404 | |
| mKIAA1215 | |
| OTTHUMP00000031861 | |
| OTTMUSP00000024060 | |
| OTTMUSP00000024061 | |
| homolog of Drosophila strabismus | |
| OTTMUSP00000041519 | |
| vang, van gogh-like 2 | |
| LPP I | |
| vang (van gogh-like 2 | |
| RIKEN cDNA C530001F03 gene | |
| vang (van gogh-like II | |
| vang-like 2 (van gogh | |
| Vangl2s | |
| loop tail | |
| vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila) | |
| vang (van gogh)-like 2 (Drosophila) | |
| vang-like 2 (van gogh, Drosophila) (predicted) | |
| Drosophila) | |
| chromosome | |
| scaffold | |
| tri | |
| trilobite | |
| vang |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus | |
| Bos taurus | |
| Danio rerio |
| OMIM ID | 600533 |
|---|
| Unigene ID | Hs.99477 |
|---|---|
| Mm.36148 | |
| Mm.392110 | |
| Rn.198958 | |
| Rn.19850 | |
| Bt.87234 | |
| Dr.114099 |
| KEGG ID | hsa:57216 |
|---|---|
| mmu:93840 | |
| rno:289229 |
| Swiss-Prot Accession | A8K4L6 |
|---|---|
| Q9ULK5 | |
| Q91ZD4 | |
| P84889 | |
| D3DVE9 | |
| Q5T212 | |
| Q923Z8 | |
| Q6ZPV8 |
| GO ID | 0007266 |
|---|---|
| 0009952 | |
| 0045176 | |
| 0035787 | |
| 0090103 | |
| 0060028 | |
| 0022007 | |
| 0048546 | |
| 0048105 | |
| 0001736 | |
| 0090177 | |
| 0045197 | |
| 0001942 | |
| 0001947 | |
| 0060122 | |
| 0060490 | |
| 0003149 | |
| 0003150 | |
| 0001843 | |
| 0035058 | |
| 0060488 | |
| 0003402 | |
| 0090179 | |
| 0060489 | |
| 0043507 | |
| 0032956 | |
| 0048103 | |
| 0035019 | |
| 0042060 | |
| 0016324 | |
| 0016323 | |
| 0060187 | |
| 0005911 | |
| 0016021 | |
| 0016328 | |
| 0060071 | |
| 0060947 | |
| 0060029 | |
| 0003347 | |
| 0090162 | |
| 0060119 | |
| 0007275 | |
| 0035567 | |
| 0003148 | |
| 0001569 | |
| 0090175 | |
| 0016020 | |
| 0005886 | |
| 0016055 | |
| 0005515 | |
| 0003674 | |
| 0008150 | |
| 0005575 | |
| 0005554 | |
| 0000132 | |
| 0000902 | |
| 0001764 | |
| 0001839 | |
| 0001841 | |
| 0007163 | |
| 0021535 | |
| 0021915 | |
| 0030010 | |
| 0030111 | |
| 0030903 | |
| 0042074 | |
| 0045810 | |
| 0045813 | |
| 0048048 | |
| 0060026 | |
| 0060027 | |
| 0060070 |
| Swiss-Prot ID | VANG2_RAT |
|---|---|
| VANG2_HUMAN | |
| VANG2_MOUSE | |
| D3DVE9_HUMAN |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00372454 |
|---|---|
| IPI00029449 | |
| IPI00154106 | |
| IPI00830187 | |
| IPI00830144 | |
| IPI00895165 |
| Mouse chromosome position | 1 93.4 cM |
|---|
| Rat chromosome position | 13q24 |
|---|
| Homologene ID | 62161 |
|---|
| MGI ID | 2135272 |
|---|---|
| 96818 | |
| 1924856 |
| RGD ID | 1309442 |
|---|
| Homo sapiens Chromosome position | 1q22-q23 |
|---|
| FunctionalClass | protein binding |
|---|---|
| molecular function unknown | |
| molecular_function |
| Mus musculus Chromosome position | 1 93.7 cM |
|---|---|
| 1 93.4 cM |
| KEGG pathway | Wnt signaling pathway |
|---|
| Rattus norvegicus Chromosome position | 13q24 |
|---|
| Bos taurus Chromosome position | 3 |
|---|