| URN | urn:agi-llid:50937 |
|---|---|
| Total Entities | 0 |
| Connectivity | 62 |
| Name | Cdon |
| Description | Cdon homolog (mouse) |
| Notes | CDON and BOC (MIM 608708) are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.[supplied by OMIM] |
| Ariadne Ontology | NEO |
|---|---|
| Oncogenes | |
| Secreted proteins |
| GO Cellular Component | membrane |
|---|---|
| extracellular matrix | |
| integral to plasma membrane | |
| integral to membrane | |
| plasma membrane | |
| cell surface |
| GO Biological Process | cell adhesion |
|---|---|
| positive regulation of small GTPase mediated signal transduction | |
| positive regulation of MAPK cascade | |
| myoblast fusion | |
| smoothened signaling pathway | |
| positive regulation of transcription from RNA polymerase II promoter | |
| positive regulation of protein phosphorylation | |
| positive regulation of neural precursor cell proliferation | |
| positive regulation of muscle cell differentiation | |
| positive regulation of neuron differentiation | |
| positive regulation of myoblast differentiation | |
| regulation of neuron differentiation | |
| cell fate specification | |
| muscle cell differentiation | |
| satellite cell differentiation | |
| striated muscle cell differentiation | |
| cell-cell adhesion | |
| regulation of striated muscle tissue development | |
| positive regulation of skeletal muscle tissue development | |
| embryonic retina morphogenesis in camera-type eye | |
| cerebral cortex development | |
| lens development in camera-type eye | |
| anterior-posterior pattern specification | |
| embryonic morphogenesis | |
| embryonic body morphogenesis | |
| regulation of protein heterodimerization activity |
| Pathway | Hedgehog signaling pathway |
|---|---|
| p38 MAPK signaling pathway | |
| p38 MAPK signaling pathway |
| Group | NEO |
|---|---|
| Oncogenes | |
| cell adhesion | |
| positive regulation of small GTPase mediated signal transduction | |
| positive regulation of MAPK cascade | |
| myoblast fusion | |
| smoothened signaling pathway | |
| positive regulation of transcription from RNA polymerase II promoter | |
| positive regulation of protein phosphorylation | |
| positive regulation of neural precursor cell proliferation | |
| positive regulation of muscle cell differentiation | |
| positive regulation of neuron differentiation | |
| positive regulation of myoblast differentiation | |
| regulation of neuron differentiation | |
| cell fate specification | |
| muscle cell differentiation | |
| satellite cell differentiation | |
| striated muscle cell differentiation | |
| cell-cell adhesion | |
| regulation of striated muscle tissue development | |
| positive regulation of skeletal muscle tissue development | |
| embryonic retina morphogenesis in camera-type eye | |
| cerebral cortex development | |
| lens development in camera-type eye | |
| anterior-posterior pattern specification | |
| embryonic morphogenesis | |
| embryonic body morphogenesis | |
| regulation of protein heterodimerization activity | |
| membrane | |
| extracellular matrix | |
| integral to plasma membrane | |
| integral to membrane | |
| plasma membrane | |
| cell surface | |
| Secreted proteins |
| MedScan ID | 50937 |
|---|
| Hugo ID | 17104 |
|---|
| Human chromosome position | 11q23-q24 |
|---|
| LocusLink ID | 50937 |
|---|---|
| 57810 | |
| 50938 |
| Alias | CDO |
|---|---|
| HPE11 | |
| ORCAM | |
| cell adhesion molecule-related/down-regulated by oncogenes | |
| surface glycoprotein, Ig superfamily member | |
| Cd0 | |
| immunoglobulin superfamily member CDO | |
| CAM-related/down-regulated by oncogenes | |
| oncogene-regulated cell adhesion molecule | |
| immunoglobulin superfamily member | |
| MGC111524 | |
| OTTMUSP00000040005 | |
| MGC129383 | |
| Cdon homolog (mouse) | |
| Cdon homolog | |
| Cdon |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 608707 |
|---|---|
| 614226 |
| Unigene ID | Hs.38034 |
|---|---|
| Mm.80509 | |
| Rn.10818 | |
| Hs.558217 |
| KEGG ID | hsa:50937 |
|---|---|
| mmu:57810 | |
| rno:50938 |
| Swiss-Prot Accession | Q4KMG0 |
|---|---|
| Q32MD9 | |
| O35158 | |
| O14631 | |
| E9QKV9 | |
| O88971 | |
| Q3TZM7 | |
| Q8CE17 |
| GO ID | 0009952 |
|---|---|
| 0007155 | |
| 0001708 | |
| 0021987 | |
| 0010172 | |
| 0060059 | |
| 0002088 | |
| 0042692 | |
| 0007520 | |
| 0043410 | |
| 0051149 | |
| 2000179 | |
| 0045666 | |
| 0001934 | |
| 0048643 | |
| 0051057 | |
| 0045944 | |
| 0043497 | |
| 0014816 | |
| 0007224 | |
| 0009986 | |
| 0031012 | |
| 0016021 | |
| 0005886 | |
| 0016337 | |
| 0048598 | |
| 0045663 | |
| 0045664 | |
| 0016202 | |
| 0051146 | |
| 0005887 | |
| 0016020 |
| PIR ID | T03096 |
|---|---|
| T03097 |
| Swiss-Prot ID | CDON_RAT |
|---|---|
| CDON_HUMAN | |
| CDON_MOUSE |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane |
| IPI ID | IPI00206284 |
|---|---|
| IPI00758456 | |
| IPI00027220 | |
| IPI00743564 | |
| IPI00136594 | |
| IPI00885462 | |
| IPI00886147 | |
| IPI00886244 | |
| IPI00885687 |
| Mouse chromosome position | 9 |
|---|
| Rat chromosome position | 8q21 |
|---|
| Homologene ID | 22996 |
|---|
| MGI ID | 1926387 |
|---|
| RGD ID | 708433 |
|---|
| Primary Cell Localization | Plasma membrane |
|---|