| URN | urn:agi-llid:663 |
|---|---|
| Total Entities | 0 |
| Connectivity | 52 |
| Name | Bnip2 |
| Description | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| Notes | This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Though the specific function is unknown, it interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. [provided by RefSeq] |
| GO Molecular Function | calcium ion binding |
|---|---|
| GTPase activator activity |
| GO Cellular Component | nuclear envelope |
|---|---|
| centriole | |
| spindle pole centrosome | |
| cytoplasm | |
| perinuclear region of cytoplasm | |
| cytosol | |
| intracellular membrane-bounded organelle |
| GO Biological Process | spindle pole body organization |
|---|---|
| positive regulation of small GTPase mediated signal transduction | |
| positive regulation of MAPK cascade | |
| positive regulation of GTPase activity | |
| negative regulation of apoptotic process | |
| positive regulation of muscle cell differentiation | |
| positive regulation of neuron differentiation | |
| muscle cell differentiation | |
| striated muscle cell differentiation | |
| apoptotic process | |
| blastocyst development |
| Pathway | p38 MAPK signaling pathway |
|---|---|
| p38 MAPK signaling pathway |
| Group | spindle pole body organization |
|---|---|
| positive regulation of small GTPase mediated signal transduction | |
| positive regulation of MAPK cascade | |
| positive regulation of GTPase activity | |
| negative regulation of apoptotic process | |
| positive regulation of muscle cell differentiation | |
| positive regulation of neuron differentiation | |
| muscle cell differentiation | |
| striated muscle cell differentiation | |
| apoptotic process | |
| blastocyst development | |
| calcium ion binding | |
| GTPase activator activity | |
| nuclear envelope | |
| centriole | |
| spindle pole centrosome | |
| cytoplasm | |
| perinuclear region of cytoplasm | |
| cytosol | |
| intracellular membrane-bounded organelle |
| MedScan ID | 663 |
|---|
| Hugo ID | 1083 |
|---|
| Human chromosome position | 15q22.2 |
|---|
| LocusLink ID | 663 |
|---|---|
| 12175 | |
| 300811 |
| Alias | NIP2 |
|---|---|
| BNIP-2 | |
| BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 | |
| Nip21 | |
| BNIP2beta | |
| 5730523P12Rik | |
| BCL2/adenovirus E1B interacting protein 1, NIP2 | |
| BCL2/adenovirus E1B 19 kDa-interacting protein 2 beta | |
| BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP2 | |
| Bcl-2 and E1B 19 kDa interacting protein | |
| Nip2l | |
| BCL2/adenovirus E1B 19-kDa protein-interactive protein II | |
| BCL2/adenovirus E1B 19kDa-interacting 1, NIP | |
| BCL2/adenovirus E1B 19kDa-interactive protein 1, NIP2 | |
| BCL2/adenovirus E1B interacting protein 2 | |
| Bnip2 | |
| 19 kDa BCL2/adenovirus E1B interacting protein 2 | |
| OTTMUSP00000040202 | |
| BCL2/adenovirus E1B 19-kDa protein-interactive protein 2 | |
| 19 kDa BCL2/adenovirus E1B interacting protein II | |
| BCL2/adenovirus E1B 19-kDa protein-interacting protein II | |
| 19 kDa BCL2/adenovirus E1B interactive protein II | |
| 5730523P12 | |
| 19 kDa BCL2/adenovirus E1B interactive protein 2 | |
| BCL2/adenovirus E1B 19kD interacting protein 2 | |
| BCL2/adenovirus E1B 19kD interacting protein II | |
| BCL2/adenovirus E1B 19kD interactive protein 2 | |
| BCL2/adenovirus E1B 19kD interactive protein II | |
| BCL2/adenovirus E1B 19kDa interacting protein 2 | |
| BNIP2alpha |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 603292 |
|---|
| Unigene ID | Hs.646490 |
|---|---|
| Mm.159777 | |
| Mm.440262 | |
| Rn.229165 | |
| Mm.479905 | |
| Rn.11821 |
| KEGG ID | hsa:663 |
|---|---|
| mmu:12175 | |
| rno:300811 |
| Swiss-Prot Accession | J3KN59 |
|---|---|
| Q12982 | |
| Q91VL0 | |
| O54940 | |
| D3ZGE0 | |
| B4DS94 | |
| Q8K4H0 | |
| Q3TTX3 | |
| Q3TWC8 | |
| Q9D632 |
| GO ID | 0005096 |
|---|---|
| 0005509 | |
| 0006915 | |
| 0042692 | |
| 0043066 | |
| 0043547 | |
| 0043410 | |
| 0051149 | |
| 0045666 | |
| 0051057 | |
| 0051146 | |
| 0005737 | |
| 0005829 | |
| 0043231 | |
| 0005635 | |
| 0048471 | |
| 0001824 | |
| 0051300 | |
| 0005814 | |
| 0031616 | |
| 0006916 |
| PIR ID | I38864 |
|---|
| Swiss-Prot ID | BNIP2_HUMAN |
|---|---|
| BNIP2_MOUSE | |
| Q91VL0_MOUSE | |
| Q8K4H0_MOUSE |
| Cell Localization | Cytoplasm |
|---|---|
| perinuclear region |
| IPI ID | IPI00030399 |
|---|---|
| IPI00943060 | |
| IPI00119891 | |
| IPI00937973 | |
| IPI00515695 | |
| IPI00331669 | |
| IPI00473381 | |
| IPI00885345 | |
| IPI00885431 | |
| IPI00373336 | |
| IPI00212492 |
| Mouse chromosome position | 9 |
|---|
| Rat chromosome position | 8q24 |
|---|
| Homologene ID | 3194 |
|---|
| MGI ID | 109327 |
|---|
| RGD ID | 1308944 |
|---|