| URN | urn:agi-llid:5603 |
|---|---|
| Total Entities | 0 |
| Connectivity | 144 |
| Name | Mapk13 |
| Description | mitogen activated protein kinase 13 |
| Notes | may play a role in stress and inflammatory responses; involved in activation of the human immunodeficiency virus gene expression [RGD] |
| Ariadne Ontology | p38 |
|---|---|
| Secreted proteins |
| GO Molecular Function | nucleotide binding |
|---|---|
| ATP binding | |
| transferase activity | |
| transferase activity, transferring phosphorus-containing groups | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity | |
| MAP kinase activity |
| GO Cellular Component | cytosol |
|---|
| GO Biological Process | cell cycle |
|---|---|
| signal transduction by phosphorylation | |
| intracellular protein kinase cascade | |
| MAPK cascade | |
| Ras protein signal transduction | |
| nerve growth factor receptor signaling pathway | |
| regulation of transcription, DNA-dependent | |
| transcription, DNA-dependent | |
| protein phosphorylation | |
| peptidyl-serine phosphorylation | |
| phosphorylation | |
| response to stress | |
| response to osmotic stress | |
| positive regulation of inflammatory response | |
| positive regulation of interleukin-6 production |
| Pathway | p38 MAPK signaling pathway |
|---|---|
| p38 MAPK signaling pathway | |
| p38 MAPK signaling pathway |
| Group | p38 |
|---|---|
| cell cycle | |
| signal transduction by phosphorylation | |
| intracellular protein kinase cascade | |
| MAPK cascade | |
| Ras protein signal transduction | |
| nerve growth factor receptor signaling pathway | |
| regulation of transcription, DNA-dependent | |
| transcription, DNA-dependent | |
| protein phosphorylation | |
| peptidyl-serine phosphorylation | |
| phosphorylation | |
| response to stress | |
| response to osmotic stress | |
| positive regulation of inflammatory response | |
| positive regulation of interleukin-6 production | |
| nucleotide binding | |
| ATP binding | |
| transferase activity | |
| transferase activity, transferring phosphorus-containing groups | |
| kinase activity | |
| protein kinase activity | |
| protein serine-threonine kinase activity | |
| MAP kinase activity | |
| cytosol | |
| Secreted proteins |
| Source | Curated |
|---|
| MedScan ID | 5603 |
|---|
| Hugo ID | 6875 |
|---|
| Human chromosome position | 6p21.31 |
|---|
| LocusLink ID | 5603 |
|---|---|
| 26415 | |
| 29513 |
| Alias | SAPK4 |
|---|---|
| PRKM13 | |
| MAPK 13 | |
| MAPK-13 | |
| p38delta | |
| RP1-179N16.4 | |
| mitogen-activated protein kinase 13 | |
| MAP kinase 13 | |
| MAP kinase p38 delta | |
| stress-activated protein kinase 4 | |
| mitogen-activated protein kinase p38 delta | |
| Serk4 | |
| RP24-313J18.2 | |
| SAPK/Erk/kinase 4 | |
| p38 delta MAP kinase | |
| mitogen activated protein kinase 13 | |
| protein kinase mitogen- activated 13 | |
| SAPK/Erk/kinase IV | |
| p38delta mitogen-activated protein kinase | |
| Stress-activated protein kinase IV | |
| SAP kinase IV | |
| SAP kinase 4 | |
| MGC99536 | |
| MAPK p38 delta | |
| MGC124619 | |
| p38 delta MAPK | |
| OTTHUMP00000016282 | |
| OTTMUSP00000028863 | |
| OTTMUSP00000028864 | |
| MAPK13 | |
| MAP kinase p38 delta | |
| Stress-activated protein kinase-4 | |
| Stress-activated protein kinase IV | |
| PRKM13s | |
| MAPK13s |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 602899 |
|---|
| Unigene ID | Hs.178695 |
|---|---|
| Mm.27970 | |
| Rn.207195 | |
| Rn.48658 |
| KEGG ID | hsa:5603 |
|---|---|
| mmu:26415 | |
| rno:29513 |
| Swiss-Prot Accession | O15264 |
|---|---|
| Q3UIB2 | |
| Q9Z1B7 | |
| Q32Q45 | |
| Q9WTY9 | |
| O14739 | |
| O15124 | |
| Q6FI46 | |
| Q9UNU0 | |
| Q99M57 | |
| Q53GK9 | |
| Q59F75 | |
| Q5R3E4 | |
| Q5R3E6 | |
| Q5U4A5 | |
| Q6FHR4 |
| EC Number | 2.7.11.24 |
|---|---|
| 2.7.1.37 |
| GO ID | 0005524 |
|---|---|
| 0004707 | |
| 0004674 | |
| 0000165 | |
| 0007265 | |
| 0007049 | |
| 0007243 | |
| 0048011 | |
| 0018105 | |
| 0050729 | |
| 0032755 | |
| 0006355 | |
| 0006970 | |
| 0006950 | |
| 0006351 | |
| 0005829 | |
| 0016301 | |
| 0000166 | |
| 0004672 | |
| 0016740 | |
| 0016772 | |
| 0016310 | |
| 0006468 | |
| 0023014 | |
| 0008339 | |
| 0005625 | |
| 0005515 | |
| 0006445 | |
| 0004713 |
| PIR ID | JC5528 |
|---|
| Swiss-Prot ID | MK13_HUMAN |
|---|---|
| MK13_MOUSE | |
| Q32Q45_RAT | |
| Q3UIB2_MOUSE | |
| Q6FI46_HUMAN |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00005741 |
|---|---|
| IPI00323424 | |
| IPI00656364 | |
| IPI00478699 | |
| IPI00604745 | |
| IPI00645543 | |
| IPI00857139 | |
| IPI00203497 |
| Mouse chromosome position | 17 |
|---|---|
| 17 A3-B |
| Rat chromosome position | 20p12 |
|---|
| Homologene ID | 48133 |
|---|
| MGI ID | 1346864 |
|---|
| RGD ID | 3045 |
|---|
| Primary Cell Localization | Cytoplasm |
|---|