| URN | urn:agi-llid:5795 |
|---|---|
| Connectivity | 109 |
| Name | Ptprj |
| Description | protein tyrosine phosphatase, receptor type, J |
| Notes | protein tyrosine phosphatase expressed in smooth muscle cells; may be involved in cell adhesion or cell-cell signaling [RGD] |
| Pathway | PTPRJ -> CTNND signaling |
|---|---|
| epidermal growth factor/neuregulin signaling pathway | |
| epidermal growth factor-neuregulin signaling pathway |
| GO Molecular Function | hydrolase activity |
|---|---|
| phosphatase activity | |
| phosphoprotein phosphatase activity | |
| protein tyrosine phosphatase activity | |
| transmembrane receptor protein tyrosine phosphatase activity | |
| receptor activity |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane | |
| nucleus | |
| cell junction | |
| integral to membrane | |
| integral to plasma membrane |
| GO Biological Process | cell-cell signaling |
|---|---|
| heart development | |
| vasculogenesis | |
| protein amino acid dephosphorylation | |
| dephosphorylation | |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| Ariadne Ontology | RPTP |
|---|---|
| Phosphatases |
| Group | RPTP |
|---|---|
| Phosphatases | |
| cell-cell signaling | |
| heart development | |
| vasculogenesis | |
| protein amino acid dephosphorylation | |
| dephosphorylation | |
| transmembrane receptor protein tyrosine kinase signaling pathway | |
| hydrolase activity | |
| phosphatase activity | |
| phosphoprotein phosphatase activity | |
| protein tyrosine phosphatase activity | |
| transmembrane receptor protein tyrosine phosphatase activity | |
| receptor activity | |
| membrane | |
| plasma membrane | |
| nucleus | |
| cell junction | |
| integral to membrane | |
| integral to plasma membrane |
| MedScan ID | 5795 |
|---|
| Hugo ID | 9673 |
|---|
| Human chromosome position | 11p11.2 |
|---|
| LocusLink ID | 5795 |
|---|---|
| 19271 | |
| 29645 |
| Alias | DEP1 |
|---|---|
| SCC1 | |
| CD148 | |
| HPTPeta | |
| R-PTP-ETA | |
| receptor-type tyrosine-protein phosphatase eta | |
| DEP-1 | |
| R-PTP-J | |
| HPTP eta | |
| CD148 antigen | |
| density-enhanced phosphatase 1 | |
| protein-tyrosine phosphatase eta | |
| human density enhanced phosphatase-1 | |
| protein-tyrosine phosphatase receptor type J | |
| susceptibility to colon cancer 1, mouse, homolog of | |
| protein tyrosine phosphatase, receptor type, J polypeptide | |
| BET | |
| Byp | |
| Ptpb2 | |
| RPTPJ | |
| Scc-1 | |
| AI450271 | |
| PTPbeta2 | |
| RP24-113P16.2 | |
| OTTMUSP00000015048 | |
| colon tumor susceptibility 1 | |
| susceptibility to colon cancer 1 | |
| HPTP beta-like tyrosine phosphatase | |
| density enhanced phosphatase-1 | |
| 2310003N02 | |
| 2310003N02Rik | |
| BET protein | |
| BET receptor | |
| BET receptors | |
| colon tumor susceptibility I | |
| colon tumour susceptibility 1 | |
| colon tumour susceptibility I | |
| Density enhanced phosphatase I | |
| DEP I | |
| HPTPETAs | |
| human density enhanced phosphatase I | |
| protein tyrosine phosphatase, receptor type, J | |
| Ptprj | |
| receptor tyrosine phosphatase eta | |
| Protein-tyrosine phosphatase eta precursor | |
| RIKEN cDNA 2310003N02 gene |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 600925 |
|---|---|
| 114500 |
| Mouse chromosome position | 2 49.5 cM |
|---|
| GO ID | 0016787 |
|---|---|
| 0005001 | |
| 0007267 | |
| 0007507 | |
| 0006470 | |
| 0007169 | |
| 0001570 | |
| 0030054 | |
| 0005887 | |
| 0005634 | |
| 0005886 | |
| 0016791 | |
| 0004721 | |
| 0004725 | |
| 0004872 | |
| 0016311 | |
| 0016021 | |
| 0016020 | |
| 0007185 |
| Rat chromosome position | 3q32-q33 |
|---|
| Swiss-Prot Accession | Q6P4H4 |
|---|---|
| Q12913 | |
| Q9NPR5 | |
| A2AWF9 | |
| Q64455 | |
| Q3V2L7 | |
| Q61373 | |
| Q62884 | |
| Q3UH64 | |
| Q3UHL5 | |
| Q541R5 | |
| Q8CIW9 | |
| Q8K3Q2 | |
| Q15255 | |
| Q8NHM2 | |
| Q9UDA9 |
| PIR ID | S68700 |
|---|---|
| I38670 |
| Unigene ID | Hs.318547 |
|---|---|
| Mm.330393 | |
| Rn.10278 |
| KEGG ID | hsa:5795 |
|---|---|
| mmu:19271 | |
| rno:29645 |
| EC Number | 3.1.3.48 |
|---|
| Swiss-Prot ID | PTPRJ_MOUSE |
|---|---|
| PTPRJ_HUMAN | |
| Q9NPR5_HUMAN | |
| Q62884_RAT | |
| Q6P4H4_HUMAN | |
| A2AWF9_MOUSE | |
| Q3UH64_MOUSE |
| Cell Localization | Membrane |
|---|---|
| Plasma membrane | |
| Cytoplasm |
| IPI ID | IPI00469426 |
|---|---|
| IPI00290328 | |
| IPI00943343 | |
| IPI00209300 | |
| IPI00847732 | |
| IPI00406609 | |
| IPI00778995 | |
| IPI00782727 | |
| IPI00780513 |
| Homologene ID | 2130 |
|---|
| RGD ID | 3454 |
|---|
| MGI ID | 104574 |
|---|