| URN | urn:agi-llid:9405 |
|---|---|
| Connectivity | 38 |
| Name | Akr1b10 |
| Description | aldo-keto reductase family 1, member B10 (aldose reductase) |
| Notes | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq] |
| Pathway | retinol metabolic pathway |
|---|
| GO Molecular Function | oxidoreductase activity |
|---|---|
| aldo-keto reductase activity |
| GO Cellular Component | cytoplasm |
|---|---|
| mitochondrion |
| GO Biological Process | digestion |
|---|---|
| oxidation reduction | |
| cellular aldehyde metabolic process | |
| steroid metabolic process |
| Ariadne Ontology | Ser-Gly metabolism |
|---|---|
| Glucose metabolism |
| Group | Ser-Gly metabolism |
|---|---|
| Glucose metabolism | |
| digestion | |
| oxidation reduction | |
| cellular aldehyde metabolic process | |
| steroid metabolic process | |
| oxidoreductase activity | |
| aldo-keto reductase activity | |
| cytoplasm | |
| mitochondrion |
| MedScan ID | 9405 |
|---|
| Hugo ID | 382 |
|---|
| Human chromosome position | 7q33 |
|---|
| LocusLink ID | 9405 |
|---|---|
| 57016 | |
| 67861 | |
| 296972 |
| Alias | HIS |
|---|---|
| HSI | |
| ARL1 | |
| ARL-1 | |
| ALDRLn | |
| AKR1B11 | |
| AKR1B12 | |
| MGC14103 | |
| aldo-keto reductase family 1 member B10 | |
| ARP | |
| hARP | |
| SI reductase | |
| aldose reductase-like 1 | |
| small intestine reductase | |
| aldose reductase-like peptide | |
| aldose reductase-related protein | |
| aldo-keto reductase family 1, member B11 (aldose reductase-like) | |
| 2310005E10Rik | |
| aldo-keto reductase family 1, member B10 | |
| OTTMUSP00000015664 | |
| OTTMUSP00000015665 | |
| 2310005E10 | |
| AKR1B10 | |
| aldo-keto reductase family 1, member B10 (aldose reductase) | |
| aldo-keto reductase family 1, member B11 | |
| aldo-keto reductase family 1, member B12 | |
| aldose reductase-like I | |
| aldose reductase-like protein | |
| androgen regulated vas deferens protein | |
| Avdp | |
| Fgfrp | |
| Fgrp | |
| FR I | |
| LOC286921 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604707 |
|---|
| Mouse chromosome position | 6 |
|---|
| GO ID | 0004033 |
|---|---|
| 0016491 | |
| 0006081 | |
| 0007586 | |
| 0055114 | |
| 0008202 | |
| 0005737 | |
| 0005739 |
| Rat chromosome position | 4q22 |
|---|
| Swiss-Prot Accession | O60218 |
|---|---|
| Q8BIV6 | |
| Q8CI22 | |
| Q8R318 | |
| Q6AY99 | |
| A4D1P1 | |
| O75890 | |
| Q6FHF3 | |
| Q8IWZ1 |
| Unigene ID | Hs.116724 |
|---|---|
| Mm.70371 | |
| Rn.8475 |
| KEGG ID | hsa:57016 |
|---|---|
| mmu:67861 | |
| rno:296972 |
| EC Number | 1.1.1.2 |
|---|---|
| 1.1.1.- |
| Swiss-Prot ID | AK1BA_HUMAN |
|---|---|
| Q6AY99_RAT | |
| Q8BIV6_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00105407 |
|---|---|
| IPI00364215 | |
| IPI00222284 | |
| IPI00750687 |
| Homologene ID | 90911 |
|---|
| RGD ID | 1308277 |
|---|
| MGI ID | 1915111 |
|---|