| URN | urn:agi-llid:53630 |
|---|---|
| Connectivity | 19 |
| Name | Bcmo1 |
| Description | beta-carotene 15,15'-monooxygenase 1 |
| Notes | Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. [provided by RefSeq] |
| Pathway | retinol metabolic pathway |
|---|
| GO Molecular Function | oxidoreductase activity |
|---|---|
| metal ion binding | |
| iron ion binding | |
| monooxygenase activity | |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | |
| beta-carotene 15,15'-monooxygenase activity |
| GO Biological Process | oxidation reduction |
|---|---|
| retinoid metabolic process |
| Group | oxidation reduction |
|---|---|
| retinoid metabolic process | |
| oxidoreductase activity | |
| metal ion binding | |
| iron ion binding | |
| monooxygenase activity | |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | |
| beta-carotene 15,15'-monooxygenase activity |
| MedScan ID | 53630 |
|---|
| Hugo ID | 13815 |
|---|
| Human chromosome position | 16q21-q23 |
|---|
| LocusLink ID | 53630 |
|---|---|
| 63857 | |
| 114106 |
| Alias | BCO |
|---|---|
| BCDO | |
| BCMO | |
| BCO1 | |
| BCDO1 | |
| FLJ10730 | |
| beta,beta-carotene 15,15'-monooxygenase | |
| beta-carotene dioxygenase 1 | |
| beta-carotene 15, 15'-dioxygenase 1 | |
| CMO1 | |
| beta-CD | |
| betaCMOOX | |
| OTTMUSP00000026605 | |
| carotenoid-15,15'-oxygenase | |
| beta-carotene cleavage enzyme | |
| beta-carotene 15,15' dioxygenase | |
| beta,beta-carotene 15,15'-dioxygenase | |
| beta-carotene 15 15-dioxygenase | |
| beta-carotene 15 15'-dioxygenase | |
| beta-carotene 15, 15-dioxygenase | |
| beta-carotene 15, 15'-dioxygenase | |
| BCDO I | |
| BCMO1 | |
| beta-carotene 15 | |
| beta-carotene 15, 15'-monooxygenase 1 | |
| beta-carotene 15,15'-monooxygenase | |
| beta-carotene 15,15'-monooxygenase I |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 605748 |
|---|---|
| 115300 |
| Mouse chromosome position | 8 |
|---|
| GO ID | 0003834 |
|---|---|
| 0046872 | |
| 0016491 | |
| 0055114 | |
| 0001523 | |
| 0004497 | |
| 0016702 | |
| 0005506 |
| Rat chromosome position | 19q12 |
|---|
| Swiss-Prot Accession | Q9HAY6 |
|---|---|
| Q05AC0 | |
| Q9JJS6 | |
| Q91XT5 | |
| Q6K1L5 | |
| Q8C6N5 | |
| Q9ERN9 | |
| A0AV48 | |
| A0AV50 | |
| Q9NVH5 |
| Unigene ID | Hs.212172 |
|---|---|
| Mm.174133 | |
| Rn.126587 |
| KEGG ID | hsa:53630 |
|---|---|
| mmu:63857 | |
| rno:114106 |
| EC Number | 1.14.99.36 |
|---|
| Swiss-Prot ID | BCDO1_MOUSE |
|---|---|
| BCDO1_RAT | |
| BCDO1_HUMAN | |
| Q05AC0_MOUSE |
| IPI ID | IPI00122199 |
|---|---|
| IPI00208162 | |
| IPI00307216 | |
| IPI00645795 |
| Homologene ID | 41172 |
|---|
| RGD ID | 70981 |
|---|
| MGI ID | 1926923 |
|---|