| URN | urn:agi-llid:84232 |
|---|---|
| Total Entities | 0 |
| Connectivity | 82 |
| Name | Maf1 |
| Description | MAF1 homolog (S. cerevisiae) |
| Notes | This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | RNA polymerase III type 1 promoter DNA binding |
|---|---|
| RNA polymerase III type 2 promoter DNA binding | |
| RNA polymerase III type 3 promoter DNA binding |
| GO Cellular Component | intracellular |
|---|---|
| plasma membrane | |
| cytoplasm | |
| cytosol | |
| nucleus | |
| axon | |
| dendrite | |
| inhibitory synapse |
| GO Biological Process | negative regulation of transcription from RNA polymerase III promoter |
|---|---|
| regulation of transcription, DNA-templated | |
| transcription, DNA-templated |
| Pathway | rRNA Transcription and Processing |
|---|---|
| tRNA Transcription and Processing | |
| RNA polymerase III transcription pathway |
| Group | negative regulation of transcription from RNA polymerase III promoter |
|---|---|
| regulation of transcription, DNA-templated | |
| transcription, DNA-templated | |
| RNA polymerase III type 1 promoter DNA binding | |
| RNA polymerase III type 2 promoter DNA binding | |
| RNA polymerase III type 3 promoter DNA binding | |
| intracellular | |
| plasma membrane | |
| cytoplasm | |
| cytosol | |
| nucleus | |
| axon | |
| dendrite | |
| inhibitory synapse |
| LocusLink ID | 84232 |
|---|---|
| 68877 | |
| 315093 |
| Cell Localization | Nucleus |
|---|---|
| Cytoplasm |
| GO ID | 0001030 |
|---|---|
| 0001031 | |
| 0001032 | |
| 0016480 | |
| 0006351 | |
| 0030424 | |
| 0005737 | |
| 0005829 | |
| 0030425 | |
| 0060077 | |
| 0005622 | |
| 0005634 | |
| 0005886 | |
| 0006355 |
| Alias | repressor of RNA polymerase III transcription MAF1 homolog |
|---|---|
| homolog of yeast MAF1 | |
| AU042856 | |
| 1110068E11Rik | |
| MAF I | |
| repressor of rna polymerase iii transcription maf1 | |
| MGC39758 | |
| MGC31779 | |
| MGC20332 | |
| MAF1 homolog (S. cerevisiae) | |
| MAF1 homolog | |
| homolog of yeast MAF I | |
| DKFZp586G1123 | |
| 1110068E11 | |
| MAF1 |
| Mouse chromosome position | 15 |
|---|
| OMIM ID | 610210 |
|---|
| Rat chromosome position | 7q34 |
|---|
| Hugo ID | 24966 |
|---|
| Human chromosome position | 8q24.3 |
|---|
| Swiss-Prot Accession | Q9H063 |
|---|---|
| Q9D0U6 | |
| Q5XIH0 | |
| Q3U4U3 | |
| Q91W84 | |
| D3DWL4 |
| Unigene ID | Hs.19673 |
|---|---|
| Mm.289680 | |
| Rn.1113 |
| KEGG ID | hsa:84232 |
|---|---|
| mmu:68877 | |
| rno:315093 |
| Swiss-Prot ID | MAF1_RAT |
|---|---|
| MAF1_MOUSE | |
| MAF1_HUMAN |
| Ensembl ID | ENSG00000179632 |
|---|---|
| ENSP00000318604 | |
| ENST00000322428 | |
| ENSMUSG00000022553 | |
| ENSMUSP00000125387 | |
| ENSMUST00000161527 | |
| ENSMUSP00000124893 | |
| ENSMUST00000160853 | |
| ENSMUSP00000023212 | |
| ENSMUST00000023212 | |
| ENSRNOG00000013514 | |
| ENSRNOP00000018240 | |
| ENSRNOT00000018240 |
| Homologene ID | 49867 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1916127 |
|---|
| RGD ID | 1359315 |
|---|
| MedScan ID | 84232 |
|---|