| URN | urn:agi-llid:5451 |
|---|---|
| Total Entities | 0 |
| Connectivity | 620 |
| Name | Pou2f1 |
| Description | POU class 2 homeobox 1 |
| Notes | The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010] |
| GO Molecular Function | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
|---|---|
| sequence-specific DNA binding transcription factor activity | |
| DNA binding | |
| sequence-specific DNA binding |
| GO Cellular Component | nucleoplasm |
|---|---|
| transcription factor complex | |
| nucleus |
| GO Biological Process | lens induction in camera-type eye |
|---|---|
| olfactory placode formation | |
| positive regulation of transcription from RNA polymerase II promoter | |
| negative regulation of transcription, DNA-templated | |
| regulation of transcription, DNA-templated | |
| transcription, DNA-templated | |
| transcription from RNA polymerase III promoter | |
| transcription from RNA polymerase II promoter | |
| gene expression |
| Pathway | RNA polymerase III transcription pathway |
|---|
| Group | Homeo/POU |
|---|---|
| lens induction in camera-type eye | |
| olfactory placode formation | |
| positive regulation of transcription from RNA polymerase II promoter | |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | |
| negative regulation of transcription, DNA-templated | |
| regulation of transcription, DNA-templated | |
| sequence-specific DNA binding transcription factor activity | |
| transcription, DNA-templated | |
| transcription from RNA polymerase III promoter | |
| transcription from RNA polymerase II promoter | |
| gene expression | |
| DNA binding | |
| sequence-specific DNA binding | |
| nucleoplasm | |
| transcription factor complex | |
| nucleus |
| LocusLink ID | 5451 |
|---|---|
| 18986 | |
| 171068 |
| Cell Localization | Nucleus |
|---|
| GO ID | 0043565 |
|---|---|
| 0003700 | |
| 0010467 | |
| 0045892 | |
| 0006383 | |
| 0005654 | |
| 0005634 | |
| 0003677 | |
| 0001077 | |
| 0060235 | |
| 0030910 | |
| 0045944 | |
| 0006355 | |
| 0006366 | |
| 0006351 | |
| 0005667 |
| Alias | OCT1 |
|---|---|
| OTF1 | |
| oct-1B | |
| POU domain, class 2, transcription factor 1 | |
| NF-A1 | |
| OTF-1 | |
| oct-1 | |
| octamer-binding protein 1 | |
| Octamer-binding transcription factor-1 | |
| octamer-binding transcription factor 1 | |
| 2810482H01Rik | |
| ubiquitous transcription factor | |
| POU domain, class 2, transcription factor | |
| POU class 2 homeobox 1 | |
| OTTHUMP00000032351 | |
| OTTHUMP00000032350 | |
| octamer transcription factor OTF1 | |
| OTF I | |
| OTTHUMP00000032348 | |
| POU domain, class 2, transcription factor I | |
| Pou2f I | |
| Oct-1 transcription factor | |
| octamer transcription factor-1 | |
| transcription factor Oct-1 | |
| transcription factor OTF1 | |
| LOC100503933 | |
| POU2F1 | |
| NF-A I | |
| Oct-1A | |
| Octamer-binding transcription factor I | |
| NFIL2A | |
| NF-IL2A | |
| oct-1z | |
| 2810482H01 | |
| Oct-1L | |
| Oct-1Cs | |
| Oct-1C | |
| Oct-1Bs | |
| Oct-1As |
| Mouse chromosome position | 1 73.21 cM |
|---|
| OMIM ID | 164175 |
|---|
| Rat chromosome position | 13q23 |
|---|
| Hugo ID | 9212 |
|---|
| Human chromosome position | 1q24.2 |
|---|
| Swiss-Prot Accession | P14859 |
|---|---|
| J3KP77 | |
| P25425 | |
| E9Q6Z8 | |
| F8VQL7 | |
| F1LRD7 | |
| P31503 | |
| Q62719 | |
| Q63387 | |
| Q61994 | |
| Q63891 | |
| Q6Y681 | |
| Q7TSD0 | |
| Q8BT04 | |
| Q8K570 | |
| Q99JH0 | |
| Q9WTZ4 | |
| Q9WTZ5 | |
| Q9WTZ6 | |
| B1AL91 | |
| B1AL93 | |
| B4E029 | |
| Q5TBT7 | |
| Q6PK46 | |
| Q8NEU9 | |
| Q9BPV1 |
| PIR ID | S16445 |
|---|---|
| S28181 | |
| I56187 | |
| S30293 | |
| A47001 |
| Unigene ID | Hs.283402 |
|---|---|
| Mm.245261 | |
| Rn.46306 |
| KEGG ID | hsa:5451 |
|---|---|
| mmu:18986 | |
| rno:171068 |
| Swiss-Prot ID | PO2F1_RAT |
|---|---|
| PO2F1_MOUSE | |
| PO2F1_HUMAN |
| Ensembl ID | ENSG00000143190 |
|---|---|
| ENSP00000356836 | |
| ENST00000367862 | |
| ENSP00000356840 | |
| ENST00000367866 | |
| ENSMUSG00000026565 | |
| ENSMUSP00000107056 | |
| ENSMUST00000111427 | |
| ENSRNOG00000003581 | |
| ENSRNOP00000044416 | |
| ENSRNOT00000047488 |
| Homologene ID | 37658 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 101898 |
|---|
| RGD ID | 621689 |
|---|
| MedScan ID | 5451 |
|---|