| URN | urn:agi-llid:1797 |
|---|---|
| Total Entities | 0 |
| Connectivity | 9 |
| Name | Dxo |
| Description | decapping exoribonuclease |
| Notes | This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | hydrolase activity |
|---|---|
| nuclease activity | |
| exonuclease activity | |
| 5'-3' exonuclease activity | |
| RNA pyrophosphohydrolase activity | |
| nucleotide binding | |
| RNA binding | |
| mRNA binding | |
| metal ion binding | |
| magnesium ion binding |
| GO Cellular Component | nucleus |
|---|
| GO Biological Process | metabolic process |
|---|---|
| RNA destabilization | |
| mRNA catabolic process | |
| nuclear mRNA surveillance | |
| nucleic acid phosphodiester bond hydrolysis |
| Pathway | RNA polymerase II transcription pathway |
|---|
| Group | Transcription factors |
|---|---|
| metabolic process | |
| RNA destabilization | |
| hydrolase activity | |
| nuclease activity | |
| exonuclease activity | |
| 5'-3' exonuclease activity | |
| RNA pyrophosphohydrolase activity | |
| mRNA catabolic process | |
| nuclear mRNA surveillance | |
| nucleic acid phosphodiester bond hydrolysis | |
| nucleotide binding | |
| RNA binding | |
| mRNA binding | |
| metal ion binding | |
| magnesium ion binding | |
| nucleus |
| LocusLink ID | 1797 |
|---|---|
| 112403 | |
| 361799 |
| Cell Localization | Nucleus |
|---|
| GO ID | 0008409 |
|---|---|
| 0034353 | |
| 0003729 | |
| 0000287 | |
| 0000166 | |
| 0050779 | |
| 0006402 | |
| 0008152 | |
| 0071028 | |
| 0090305 | |
| 0005634 | |
| 0003723 | |
| 0004527 | |
| 0016787 | |
| 0046872 | |
| 0004518 |
| Alias | NG6 |
|---|---|
| RAI1 | |
| DOM3L | |
| DOM3Z | |
| DAMC-178C20.2 | |
| decapping and exoribonuclease protein | |
| protein Dom3Z | |
| decapping exoribonuclease | |
| OTTHUMP00000216105 | |
| OTTHUMP00000174711 | |
| OTTHUMP00000062703 | |
| OTTHUMP00000029408 | |
| MGC95256 | |
| dom-3 homolog Z (C. elegans) | |
| OTTHUMP00000029410 | |
| DOM-3 homolog Z | |
| DOM-3 homolog Z isoform 1 | |
| DOM-3 homolog Z isoform 2 | |
| DOM-3 homolog Z isoform I | |
| DOM-3 homolog Z isoform II | |
| DOM-3 (C. elegans) homolog Z |
| Mouse chromosome position | 17 |
|---|
| OMIM ID | 605996 |
|---|
| Rat chromosome position | 20p12 |
|---|
| Hugo ID | 2992 |
|---|
| Human chromosome position | 6p21.3 |
|---|
| Swiss-Prot Accession | O77932 |
|---|---|
| O70348 | |
| Q6MG77 | |
| Q99KD8 | |
| A2CER3 | |
| B0UZ80 | |
| O15004 | |
| O78127 | |
| O78128 | |
| Q5ST60 | |
| Q6IPZ2 | |
| Q9NPK4 |
| Unigene ID | Hs.153299 |
|---|---|
| Mm.275309 | |
| Rn.20463 |
| KEGG ID | hsa:1797 |
|---|---|
| mmu:112403 | |
| rno:361799 |
| Swiss-Prot ID | DXO_MOUSE |
|---|---|
| DXO_HUMAN | |
| DXO_RAT |
| EC Number | 3.1.13.- |
|---|---|
| 3.6.1.- |
| Ensembl ID | ENSG00000204348 |
|---|---|
| ENSP00000337759 | |
| ENST00000337523 | |
| ENSMUSG00000040482 | |
| ENSMUSP00000137234 | |
| ENSMUST00000180043 | |
| ENSMUSP00000047018 | |
| ENSMUST00000046244 | |
| ENSRNOG00000000422 | |
| ENSRNOP00000000483 | |
| ENSRNOT00000000483 |
| Homologene ID | 38061 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1890444 |
|---|
| RGD ID | 1303267 |
|---|
| MedScan ID | 1797 |
|---|