| URN | urn:agi-llid:4691 |
|---|---|
| Total Entities | 0 |
| Connectivity | 708 |
| Name | Ncl |
| Description | nucleolin |
| Notes | Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | protein C-terminus binding |
|---|---|
| nucleotide binding | |
| nucleic acid binding | |
| RNA binding | |
| DNA binding | |
| telomeric DNA binding |
| GO Cellular Component | nucleoplasm |
|---|---|
| nucleolus | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cell cortex | |
| nucleus |
| GO Biological Process | angiogenesis |
|---|
| Pathway | IL2 Expression Targets |
|---|---|
| FGF2/AP-1/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| FGF2/STAT Expression Targets | |
| RNA polymerase I transcription pathway | |
| RNA polymerase I transcription pathway |
| Group | Nucleolus organization and biogenesis |
|---|---|
| angiogenesis | |
| protein C-terminus binding | |
| nucleotide binding | |
| nucleic acid binding | |
| RNA binding | |
| DNA binding | |
| telomeric DNA binding | |
| nucleoplasm | |
| nucleolus | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cell cortex | |
| nucleus | |
| Secreted proteins | |
| Biofluids assayable substances |
| LocusLink ID | 4691 |
|---|---|
| 17975 | |
| 25135 |
| Cell Localization | Nucleus |
|---|---|
| Nucleolus | |
| Cytoplasm |
| GO ID | 0003723 |
|---|---|
| 0000166 | |
| 0008022 | |
| 0042162 | |
| 0001525 | |
| 0005938 | |
| 0005730 | |
| 0005654 | |
| 0005634 | |
| 0030529 | |
| 0003677 | |
| 0003676 | |
| 0005737 |
| Alias | C23 |
|---|---|
| nucleolin | |
| Nucl | |
| D0Nds28 | |
| D1Nds28 | |
| B530004O11Rik | |
| nucleolin-like protein | |
| Nuc | |
| protein c23 | |
| MGC93572 | |
| B530004O11 | |
| RIKEN cDNA B530004O11 gene | |
| nucleolus protein c23 | |
| nucleolar protein c23 | |
| NUCL_HUMAN | |
| LOC100289394 | |
| FLJ45706 | |
| FLJ59041 | |
| phosphoprotein c23 | |
| LOC100361152 |
| Mouse chromosome position | 1 43.94 cM |
|---|---|
| 1 48.4 cM |
| OMIM ID | 164035 |
|---|
| Rat chromosome position | 9q35 |
|---|
| Hugo ID | 7667 |
|---|
| Human chromosome position | 2q37.1 |
|---|
| Swiss-Prot Accession | B3KM80 |
|---|---|
| P19338 | |
| Q9BQ02 | |
| P09405 | |
| Q5U328 | |
| P13383 | |
| Q53SK1 | |
| Q8NB06 | |
| Q9UCF0 | |
| Q9UDG1 | |
| Q548M9 | |
| Q61991 | |
| Q8BQD8 | |
| Q99K50 |
| PIR ID | A35804 |
|---|---|
| S53728 | |
| A29958 |
| Unigene ID | Hs.79110 |
|---|---|
| Mm.154378 | |
| Mm.474153 | |
| Rn.144561 | |
| Rn.7735 |
| KEGG ID | hsa:4691 |
|---|---|
| mmu:17975 | |
| rno:25135 |
| Swiss-Prot ID | NUCL_HUMAN |
|---|---|
| NUCL_MOUSE |
| Ensembl ID | ENSMUSG00000026234 |
|---|---|
| ENSMUSP00000027438 | |
| ENSMUST00000027438 | |
| ENSRNOG00000018273 | |
| ENSRNOP00000024712 | |
| ENSRNOT00000024712 |
| Homologene ID | 21821 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 97286 |
|---|
| RGD ID | 3153 |
|---|
| MedScan ID | 4691 |
|---|---|
| 17975 |
| Primary Cell Localization | Nucleus |
|---|
| IPI ID | IPI00317794 |
|---|---|
| IPI00604620 |