| URN | urn:agi-llid:4691 |
|---|---|
| Total Entities | 0 |
| Connectivity | 438 |
| Name | Ncl |
| Description | nucleolin |
| Notes | Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20. [provided by RefSeq, Jul 2008] |
| Ariadne Ontology | Nucleolus organization and biogenesis |
|---|---|
| Biofluids assayable substances |
| GO Molecular Function | protein C-terminus binding |
|---|---|
| nucleotide binding | |
| nucleic acid binding | |
| RNA binding | |
| DNA binding | |
| telomeric DNA binding |
| GO Cellular Component | nucleoplasm |
|---|---|
| nucleolus | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cell cortex | |
| nucleus |
| GO Biological Process | angiogenesis |
|---|
| Pathway | IL2 Expression Targets |
|---|---|
| FGF2/AP-1/CREB/CREBBP/ELK-SRF/MYC Expression Targets | |
| FGF2/STAT Expression Targets | |
| RNA polymerase I transcription pathway |
| Group | Nucleolus organization and biogenesis |
|---|---|
| angiogenesis | |
| protein C-terminus binding | |
| nucleotide binding | |
| nucleic acid binding | |
| RNA binding | |
| DNA binding | |
| telomeric DNA binding | |
| nucleoplasm | |
| nucleolus | |
| ribonucleoprotein complex | |
| cytoplasm | |
| cell cortex | |
| nucleus | |
| Biofluids assayable substances |
| MedScan ID | 4691 |
|---|---|
| 17975 |
| Hugo ID | 7667 |
|---|
| Human chromosome position | 2q37.1 |
|---|
| LocusLink ID | 4691 |
|---|---|
| 17975 | |
| 25135 |
| Alias | C23 |
|---|---|
| nucleolin | |
| Nucl | |
| D0Nds28 | |
| D1Nds28 | |
| B530004O11Rik | |
| nucleolin-like protein | |
| Nuc | |
| NUCL_HUMAN | |
| LOC100361152 | |
| LOC100289394 | |
| FLJ45706 | |
| FLJ59041 | |
| MGC93572 | |
| B530004O11 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 164035 |
|---|
| Unigene ID | Hs.79110 |
|---|---|
| Mm.154378 | |
| Mm.474153 | |
| Rn.7735 | |
| Rn.144561 |
| KEGG ID | hsa:4691 |
|---|---|
| mmu:17975 | |
| rno:25135 |
| Swiss-Prot Accession | B3KM80 |
|---|---|
| P19338 | |
| P09405 | |
| Q5U328 | |
| P13383 | |
| Q548M9 | |
| Q61991 | |
| Q8BQD8 | |
| Q99K50 | |
| Q53SK1 | |
| Q8NB06 | |
| Q9UCF0 | |
| Q9UDG1 |
| GO ID | 0003723 |
|---|---|
| 0000166 | |
| 0008022 | |
| 0042162 | |
| 0001525 | |
| 0005938 | |
| 0005730 | |
| 0005654 | |
| 0005634 | |
| 0030529 | |
| 0003677 | |
| 0003676 | |
| 0005737 |
| PIR ID | A29958 |
|---|---|
| A35804 | |
| S53728 |
| Swiss-Prot ID | NUCL_MOUSE |
|---|---|
| NUCL_HUMAN |
| Cell Localization | Nucleus |
|---|---|
| nucleolus | |
| Cytoplasm |
| IPI ID | IPI00317794 |
|---|---|
| IPI00604620 |
| Mouse chromosome position | 1 48.4 cM |
|---|
| Rat chromosome position | 9q35 |
|---|
| Homologene ID | 21821 |
|---|
| MGI ID | 97286 |
|---|
| RGD ID | 3153 |
|---|
| Primary Cell Localization | Nucleus |
|---|