| URN | urn:agi-llid:55733 |
|---|---|
| Connectivity | 21 |
| Name | HHAT |
| Description | hedgehog acyltransferase |
| Notes | 'Skinny hedgehog' (SKI1) encodes an enzyme that acts within the secretory pathway to catalyze amino-terminal palmitoylation of 'hedgehog' (see MIM 600725).[supplied by OMIM] |
| Pathway | Hedgehog signaling pathway |
|---|
| GO Molecular Function | nucleotide binding |
|---|---|
| transferase activity | |
| GTP binding | |
| acyltransferase activity | |
| palmitoyltransferase activity |
| GO Cellular Component | membrane |
|---|---|
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| integral to membrane |
| GO Biological Process | multicellular organismal development |
|---|---|
| protein palmitoylation | |
| smoothened signaling pathway |
| Group | multicellular organismal development |
|---|---|
| protein palmitoylation | |
| smoothened signaling pathway | |
| nucleotide binding | |
| transferase activity | |
| GTP binding | |
| acyltransferase activity | |
| palmitoyltransferase activity | |
| membrane | |
| endoplasmic reticulum membrane | |
| endoplasmic reticulum | |
| integral to membrane |
| MedScan ID | 55733 |
|---|
| Hugo ID | 18270 |
|---|
| Human chromosome position | 1q32 |
|---|
| LocusLink ID | 55733 |
|---|---|
| 226861 |
| Alias | Skn |
|---|---|
| SKI1 | |
| MART2 | |
| FLJ10724 | |
| FLJ34867 | |
| protein-cysteine N-palmitoyltransferase HHAT | |
| OTTHUMP00000034611 | |
| skinny hedgehog protein 1 | |
| melanoma antigen recognized by T cells 2 | |
| melanoma antigen recognized by T-cells 2 | |
| AI462858 | |
| MGC11697 | |
| 2810432O22Rik | |
| AC115917.1 | |
| OTTMUSP00000033669 | |
| skinny hedgehog protein | |
| 2810432O22 | |
| hedgehog acyltransferase | |
| hhat | |
| homolog of Drosophila skinny hedgehog, | |
| melanoma antigen recognized by T cells II | |
| OTTHUMP00000034608 | |
| SKI | |
| skinny hedgehog, Drosophila, homolog of |
| Organism | Homo sapiens |
|---|---|
| Mus musculus |
| OMIM ID | 605743 |
|---|
| Mouse chromosome position | 1 |
|---|
| GO ID | 0005525 |
|---|---|
| 0008415 | |
| 0000166 | |
| 0016740 | |
| 0007275 | |
| 0005783 | |
| 0005789 | |
| 0016021 | |
| 0016020 | |
| 0016409 | |
| 0018345 | |
| 0007224 |
| Swiss-Prot Accession | Q05BM0 |
|---|---|
| Q5VTY9 | |
| Q8BMT9 | |
| Q3TQW5 | |
| Q8BWF5 | |
| Q17RZ7 | |
| Q4G0K3 | |
| Q5CZ95 | |
| Q5TGI2 | |
| Q9NVH9 | |
| Q9Y3N8 | |
| B1ANS0 | |
| Q3TA33 | |
| Q922G3 | |
| B7Z4D5 | |
| B7Z868 | |
| B7Z5I1 | |
| D3DT91 | |
| B7Z5N1 |
| Unigene ID | Hs.58650 |
|---|---|
| Mm.145857 |
| KEGG ID | hsa:55733 |
|---|---|
| mmu:226861 |
| EC Number | 2.3.1.- |
|---|
| Swiss-Prot ID | HHAT_HUMAN |
|---|---|
| HHAT_MOUSE | |
| B7Z4D5_HUMAN | |
| B7Z868_HUMAN | |
| B7Z5I1_HUMAN | |
| D3DT91_HUMAN | |
| B7Z5N1_HUMAN | |
| B1ANS0_MOUSE |
| Cell Localization | Endoplasmic reticulum membrane |
|---|
| IPI ID | IPI00018902 |
|---|---|
| IPI00163890 | |
| IPI00657747 | |
| IPI00923457 | |
| IPI00223115 | |
| IPI00670095 | |
| IPI00922056 | |
| IPI00554791 | |
| IPI00653855 | |
| IPI00473977 | |
| IPI00856718 | |
| IPI00856955 |
| Homologene ID | 41232 |
|---|
| RGD ID | 1351064 |
|---|
| MGI ID | 2444681 |
|---|