| URN | urn:agi-llid:666 |
|---|---|
| Connectivity | 23 |
| Name | Bok |
| Description | BCL2-related ovarian killer |
| Notes | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2 protein identified in the ovary. |
| Pathway | Apoptosis |
|---|---|
| intrinsic apoptotic pathway |
| GO Molecular Function | BH domain binding |
|---|---|
| protein heterodimerization activity |
| GO Biological Process | positive regulation of apoptosis |
|---|---|
| induction of apoptosis | |
| regulation of apoptosis | |
| apoptosis |
| Group | positive regulation of apoptosis |
|---|---|
| induction of apoptosis | |
| regulation of apoptosis | |
| apoptosis | |
| BH domain binding | |
| protein heterodimerization activity |
| MedScan ID | 666 |
|---|
| Hugo ID | 1087 |
|---|
| Human chromosome position | 2q37.3 |
|---|
| LocusLink ID | 666 |
|---|---|
| 51800 | |
| 29884 |
| Alias | BOKL |
|---|---|
| BCL2L9 | |
| MGC4631 | |
| bcl-2-related ovarian killer protein | |
| hBOK | |
| bcl2-L-9 | |
| bcl-2-like protein 9 | |
| mtd | |
| matador | |
| AI847676 | |
| AU021146 | |
| protein matador | |
| apoptosis activator Mtd | |
| Bcl-2-related ovarian killer protein-like | |
| BCL2-related ovarian killer | |
| Bok | |
| matadors | |
| BCL2-related ovarian killer protein | |
| apoptosis activator |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 605404 |
|---|
| Mouse chromosome position | 1 |
|---|---|
| 1 D |
| GO ID | 0051400 |
|---|---|
| 0046982 | |
| 0006915 | |
| 0006917 | |
| 0043065 | |
| 0042981 | |
| 0046983 | |
| 0005575 |
| Rat chromosome position | 9q36 |
|---|
| Swiss-Prot Accession | Q9UMX3 |
|---|---|
| Q53NU8 | |
| Q53QM7 | |
| Q9UL32 | |
| O35425 | |
| Q3TH93 | |
| Q792S6 | |
| O88857 |
| Unigene ID | Hs.293753 |
|---|---|
| Mm.3295 | |
| Rn.44461 |
| KEGG ID | hsa:666 |
|---|---|
| mmu:51800 | |
| rno:29884 |
| Swiss-Prot ID | BOK_RAT |
|---|---|
| BOK_MOUSE | |
| BOK_HUMAN | |
| Q3TH93_MOUSE |
| IPI ID | IPI00209364 |
|---|---|
| IPI00213389 | |
| IPI00130704 | |
| IPI00000133 | |
| IPI00003307 |
| Homologene ID | 9632 |
|---|
| RGD ID | 70984 |
|---|
| MGI ID | 1858494 |
|---|