| URN | urn:agi-llid:1938 |
|---|---|
| Total Entities | 0 |
| Connectivity | 404 |
| Name | Eef2 |
| Description | eukaryotic translation elongation factor 2 |
| Notes | This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | GTPase activity |
|---|---|
| translation elongation factor activity | |
| nucleotide binding | |
| GTP binding |
| GO Cellular Component | ribonucleoprotein complex |
|---|---|
| polysome | |
| cytoplasm | |
| cytosol |
| GO Biological Process | GTP catabolic process |
|---|---|
| cellular protein metabolic process | |
| translation | |
| translational elongation | |
| gene expression |
| Pathway | Translation |
|---|---|
| translation pathway |
| Group | Translation |
|---|---|
| GTP catabolic process | |
| GTPase activity | |
| cellular protein metabolic process | |
| translation | |
| translational elongation | |
| translation elongation factor activity | |
| gene expression | |
| nucleotide binding | |
| GTP binding | |
| ribonucleoprotein complex | |
| polysome | |
| cytoplasm | |
| cytosol | |
| Secreted proteins | |
| Biofluids assayable substances |
| LocusLink ID | 1938 |
|---|---|
| 13629 | |
| 29565 |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0005525 |
|---|---|
| 0003924 | |
| 0003746 | |
| 0044267 | |
| 0010467 | |
| 0006412 | |
| 0006414 | |
| 0005829 | |
| 0005844 | |
| 0030529 | |
| 0000166 | |
| 0006184 | |
| 0005737 |
| Alias | EF2 |
|---|---|
| EF-2 | |
| EEF-2 | |
| SCA26 | |
| elongation factor 2 | |
| polypeptidyl-tRNA translocase | |
| elongation factor-2 | |
| eukaryotic translation elongating factor II | |
| elongation factor ef 2 | |
| SD04694p | |
| MGC98463 | |
| eukaryotic translation elongation factor II | |
| eukaryotic translation elongation factor 2 | |
| peptide elongation factor 2 | |
| eukaryotic translation elongating factor 2 | |
| elongation factor-2 (Tanystylum orbiculare) | |
| Elongation factor II | |
| elongating factor-2 (Tanystylum orbiculare) | |
| e-EF2 | |
| Eef2 |
| Mouse chromosome position | 10 |
|---|
| OMIM ID | 130610 |
|---|---|
| 609306 |
| Rat chromosome position | 7q11 |
|---|
| Hugo ID | 3214 |
|---|
| Human chromosome position | 19p13.3 |
|---|
| Swiss-Prot Accession | P13639 |
|---|---|
| B4DPU3 | |
| P58252 | |
| P05197 | |
| B2RMP5 | |
| D6W618 | |
| Q58J86 | |
| Q544E4 | |
| P97619 |
| PIR ID | S18294 |
|---|---|
| S04007 |
| Unigene ID | Hs.515070 |
|---|---|
| Mm.326799 | |
| Mm.482883 | |
| Mm.486637 | |
| Rn.55145 |
| KEGG ID | hsa:1938 |
|---|---|
| mmu:13629 | |
| rno:29565 |
| Swiss-Prot ID | EF2_HUMAN |
|---|---|
| EF2_MOUSE | |
| EF2_RAT |
| Ensembl ID | ENSG00000167658 |
|---|---|
| ENSP00000307940 | |
| ENST00000309311 | |
| ENSMUSG00000034994 | |
| ENSMUSP00000046101 | |
| ENSMUST00000047864 | |
| ENSRNOG00000020266 | |
| ENSRNOP00000041821 | |
| ENSRNOT00000047450 |
| Homologene ID | 100816 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 95288 |
|---|
| RGD ID | 61979 |
|---|
| MedScan ID | 1938 |
|---|