Protein Eif5

URN urn:agi-llid:1983
Total Entities 0
Connectivity 84
Name Eif5
Description eukaryotic translation initiation factor 5
Notes Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

GO Molecular Function GTPase activity
translation initiation factor activity
translation factor activity, nucleic acid binding
nucleotide binding
GTP binding

GO Cellular Component cytoplasm
cytosol

GO Biological Process GTP catabolic process
regulation of translational initiation
translational initiation
cellular protein metabolic process
translation
gene expression

Pathway translation pathway

Group GTP catabolic process
GTPase activity
regulation of translational initiation
translational initiation
translation initiation factor activity
cellular protein metabolic process
translation
translation factor activity, nucleic acid binding
gene expression
nucleotide binding
GTP binding
cytoplasm
cytosol

LocusLink ID 1983
217869
56783

GO ID 0005525
0003924
0008135
0003743
0006184
0044267
0010467
0006446
0006412
0006413
0005737
0005829
0000166

Alias EIF-5
EIF-5A
eukaryotic translation initiation factor 5
D12Ertd549e
2810011H21Rik
eukaryotic initiation factor 5 (eIF-5)
RIKEN cDNA 2810011H21 gene
eukaryotic initiation factor V
initiation factor 5
MGC36509
MGC36374
Eukaryotic translation initiation factor V
initiation factor eIF 5
eukaryotic initiation factor 5
Eif5
DNA segment, Chr 12, ERATO Doi 549, expressed
2810011H21
Eukaryotic translation initiating factor V
Eukaryotic translation initiating factor 5

Mouse chromosome position 12 61.03 cM

OMIM ID 601710

Rat chromosome position 6q32

Hugo ID 3299

Human chromosome position 14q32.32

Swiss-Prot Accession P55010
Q6IBU0
P59325
Q3TQR3
Q07205
Q53XB3
Q9H5N2
Q9UG48

PIR ID A47305
T12450

GenBank ID NC_000014
NM_001969
NP_001960
XM_005267395
XP_005267452
NM_183004
NP_892116
NC_018925
AC_000146
ABBA01048430
ABBA01048431
AL138976
AMYH02029922
CH471061
EAW81808
EAW81809
EAW81810
EAW81811
AK026933
BAB15593
AK027240
AK074470
AK293712
BAG57144
AL080102
CAB45711
BC000106
BC007728
AAH07728
BC015630
AAH15630
BC032866
AAH32866
BC041083
BC107884
AAI07885
BF979642
BI459720
BX429104
BX537367
CAD97610
CR456712
CAG32993
CR627002
DB458085
U49436
AAC50572
P55010
DQ893482
ABM84408
EU832284
ACE87541
EU832369
ACE86854
HQ448292
ADQ32772
NC_000078
NM_173363
NP_775539
NM_178041
NP_829887
AC_000034
AAHY01103563
AC163357
CH466549
EDL18629
AI391022
AK012708
AK051980
AK076403
BAC36325
AK076694
AK159232
BAE34918
AK160828
AK160879
AK161554
BAE36460
AK163368
BAE37319
AK166775
BAE39011
AK167331
BAE39433
AK172048
BAE42798
AK182296
AK212690
AK216620
AK218038
AW547465
BC012220
BC019769
AAH19769
BC023074
AAH23074
BC023169
BC025523
AAH25523
BC025557
AAH25557
BC029003
AAH29003
BC029628
BC039275
AAH39275
BC042622
BC056633
AAH56633
BQ175483
P59325
NC_005105
XM_006240608
XP_006240670
XM_006240609
XP_006240671
NM_020075
NP_064460
AC_000074
AABR06046323
AAHX01046683
AAHX01046684
CH474034
EDL97465
BC062398
AAH62398
FQ210184
FQ210259
FQ210384
FQ210656
FQ210682
FQ211163
FQ211171
FQ211402
FQ211468
FQ211474
FQ211551
FQ212296
FQ212334
FQ212345
FQ216911
FQ217118
FQ217366
FQ217462
FQ217871
FQ218204
FQ221098
FQ221133
FQ221190
FQ221193
FQ221214
FQ221235
FQ221240
FQ221274
FQ221291
FQ221336
FQ221426
FQ221574
FQ221575
FQ221599
FQ221687
FQ221853
FQ222051
FQ222078
FQ222175
FQ222229
FQ222254
FQ222258
FQ222267
FQ222325
FQ222330
FQ222337
FQ222517
FQ222715
FQ222912
FQ222978
FQ223113
FQ223248
FQ223260
FQ223293
FQ223338
FQ223370
FQ223383
FQ223401
FQ223435
FQ223474
FQ223834
FQ224008
FQ224071
FQ224305
FQ224350
FQ224517
FQ224561
FQ225790
FQ226158
FQ226589
FQ228260
FQ228310
FQ228330
FQ228340
FQ228343
FQ228637
FQ228643
FQ228647
FQ228649
FQ230506
L11651
AAA41112
Q07205

Unigene ID Hs.433702
Hs.741278
Mm.271222
Mm.470192
Rn.40123

KEGG ID hsa:1983
mmu:217869
rno:56783

Swiss-Prot ID IF5_RAT
IF5_HUMAN

Ensembl ID ENSG00000100664
ENSP00000216554
ENST00000216554
ENSP00000453743
ENST00000558506
ENSMUSG00000021282
ENSMUSP00000126825
ENSMUST00000166123
ENSRNOG00000010218
ENSRNOP00000013695
ENSRNOT00000013695

Homologene ID 49610

Organism Homo sapiens
Mus musculus
Rattus norvegicus

MGI ID 95309

RGD ID 619861

MedScan ID 1983