| URN | urn:agi-llid:64064 |
|---|---|
| Connectivity | 0 |
| Name | Oxct2a |
| Description | 3-oxoacid CoA transferase 2 |
| Notes | OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization. See also OXCT1 (MIM 601424).[supplied by OMIM] |
| Pathway | ketone bodies metabolic pathway |
|---|
| Ariadne Ontology | Branced aminoacid metabolism |
|---|
| GO Molecular Function | transferase activity |
|---|---|
| CoA-transferase activity | |
| 3-oxoacid CoA-transferase activity |
| GO Cellular Component | microtubule-based flagellum |
|---|---|
| mitochondrion |
| GO Biological Process | metabolic process |
|---|---|
| generation of precursor metabolites and energy | |
| cellular ketone body metabolic process | |
| ketone body catabolic process | |
| succinyl-CoA metabolic process |
| Group | Branced aminoacid metabolism |
|---|---|
| microtubule-based flagellum | |
| mitochondrion | |
| transferase activity | |
| CoA-transferase activity | |
| 3-oxoacid CoA-transferase activity | |
| metabolic process | |
| generation of precursor metabolites and energy | |
| cellular ketone body metabolic process | |
| ketone body catabolic process | |
| succinyl-CoA metabolic process |
| Hugo ID | 18606 |
|---|
| Human chromosome position | 1p34 |
|---|
| LocusLink ID | 64064 |
|---|---|
| 64059 | |
| 353371 | |
| 366463 |
| Alias | FKSG25 |
|---|---|
| SCOT-T | |
| FLJ00030 | |
| 3-oxoacid CoA transferase 2 | |
| OTTHUMP00000010841 | |
| Oxct | |
| Scot | |
| Oxct2 | |
| Scot-t1 | |
| RP23-25K8.2 | |
| 3-oxoacid CoA transferase 2A | |
| OTTMUSP00000009346 | |
| succinyl-CoA:3-oxoacid CoA-transferase | |
| haploid germ cell specific succinyl CoA transferase | |
| Scot-t2 | |
| MGC130507 | |
| RP23-138L21.2 | |
| 3-oxoacid CoA transferase 2B | |
| OTTMUSP00000009308 | |
| succinyl CoA:3-oxoacid CoA-transferase | |
| 3-oxoacid CoA transferase II | |
| Scot-t I | |
| Oxct2a | |
| Oxct2b | |
| LOC112469 | |
| LOC112470 | |
| LOC115689 | |
| LOC115690 | |
| LOC194195 | |
| succinyl-CoA:3-oxoacid CoA-transferase 2 | |
| LOC92407 | |
| FKSG25s |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 610289 |
|---|
| Swiss-Prot Accession | Q9BYC2 |
|---|---|
| Q6INA3 | |
| Q9H7N8 | |
| Q9JJN4 | |
| Q8K4T9 | |
| Q9ESL0 | |
| Q5XIJ9 |
| Unigene ID | Hs.472491 |
|---|---|
| Mm.270287 | |
| Mm.189660 | |
| Rn.110620 |
| KEGG ID | hsa:64064 |
|---|---|
| mmu:64059 | |
| mmu:353371 | |
| rno:366463 |
| EC Number | 2.8.3.5 |
|---|
| Swiss-Prot ID | SCO2A_MOUSE |
|---|---|
| SCO2A_RAT | |
| SCO2B_MOUSE | |
| SCOT2_HUMAN | |
| B9EHG5_MOUSE |
| Cell Localization | Cytoplasm |
|---|
| GO ID | 0008260 |
|---|---|
| 0016740 | |
| 0046952 | |
| 0008152 | |
| 0009434 | |
| 0005739 | |
| 0008410 | |
| 0046950 | |
| 0006104 | |
| 0006091 |
| IPI ID | IPI00307395 |
|---|---|
| IPI00450348 | |
| IPI00739583 | |
| IPI00276577 | |
| IPI00387281 | |
| IPI00359138 |
| Mouse chromosome position | 4 D2.2 |
|---|
| MGI ID | 1891061 |
|---|---|
| 2664115 |
| Rat chromosome position | 5q36 |
|---|
| RGD ID | 1306953 |
|---|