| URN | urn:agi-llid:65985 |
|---|---|
| Connectivity | 9 |
| Name | Aacs |
| Description | acetoacetyl-CoA synthetase |
| Notes | activates acetoacetate to its CoA ester [RGD] |
| Pathway | ketone bodies metabolic pathway |
|---|
| GO Molecular Function | catalytic activity |
|---|---|
| ligase activity | |
| acetoacetate-CoA ligase activity |
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol |
| GO Biological Process | metabolic process |
|---|---|
| positive regulation of insulin secretion | |
| white fat cell differentiation | |
| fatty acid metabolic process | |
| liver development | |
| lipid metabolic process | |
| response to drug | |
| response to nutrient | |
| response to ethanol | |
| response to organic nitrogen | |
| response to organic cyclic substance | |
| response to oleic acid |
| Group | cytoplasm |
|---|---|
| cytosol | |
| catalytic activity | |
| ligase activity | |
| acetoacetate-CoA ligase activity | |
| metabolic process | |
| positive regulation of insulin secretion | |
| white fat cell differentiation | |
| fatty acid metabolic process | |
| liver development | |
| lipid metabolic process | |
| response to drug | |
| response to nutrient | |
| response to ethanol | |
| response to organic nitrogen | |
| response to organic cyclic substance | |
| response to oleic acid |
| Hugo ID | 21298 |
|---|
| Human chromosome position | 12q24.31 |
|---|
| LocusLink ID | 65985 |
|---|---|
| 78894 | |
| 65984 |
| Alias | ACSF1 |
|---|---|
| SUR-5 | |
| FLJ12389 | |
| FLJ41251 | |
| acetoacetyl-CoA synthetase | |
| acetoacetate-CoA ligase | |
| acyl-CoA synthetase family member 1 | |
| homolog of C. elegans supressor of ras 5 (sur-5) | |
| SUR5 | |
| 2210408B16Rik | |
| OTTMUSP00000027664 | |
| RIKEN cDNA 2210408B16 gene | |
| acetoacetate-CoA ligases | |
| AACS | |
| homolog of c. elegans supressor of ras V | |
| homolog of c. elegans supressor of ras 5 | |
| LOC65984 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| Swiss-Prot Accession | Q86V21 |
|---|---|
| Q49AJ4 | |
| Q9H7A6 | |
| Q9H9K9 | |
| Q9D2R0 | |
| Q8K3J7 | |
| Q9JMI1 |
| Unigene ID | Hs.656073 |
|---|---|
| Mm.439974 | |
| Rn.9215 |
| KEGG ID | hsa:65985 |
|---|---|
| rno:65984 |
| EC Number | 6.2.1.16 |
|---|
| Swiss-Prot ID | AACS_HUMAN |
|---|---|
| AACS_MOUSE | |
| AACS_RAT |
| GO ID | 0030729 |
|---|---|
| 0016874 | |
| 0006631 | |
| 0006629 | |
| 0008152 | |
| 0005737 | |
| 0003824 | |
| 0001889 | |
| 0032024 | |
| 0042493 | |
| 0045471 | |
| 0007584 | |
| 0034201 | |
| 0014070 | |
| 0010243 | |
| 0050872 | |
| 0005829 |
| IPI ID | IPI00217272 |
|---|---|
| IPI00646775 | |
| IPI00789348 | |
| IPI00334184 | |
| IPI00790421 | |
| IPI00788607 | |
| IPI00135189 | |
| IPI00204738 |
| Mouse chromosome position | 5 F |
|---|
| Homologene ID | 11322 |
|---|
| MGI ID | 1926144 |
|---|
| Rat chromosome position | 12q14 |
|---|
| RGD ID | 708522 |
|---|