| URN | urn:agi-llid:622 |
|---|---|
| Connectivity | 17 |
| Name | Bdh1 |
| Description | 3-hydroxybutyrate dehydrogenase, type 1 |
| Notes | This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq] |
| Pathway | ketone bodies metabolic pathway |
|---|
| GO Molecular Function | binding |
|---|---|
| catalytic activity | |
| oxidoreductase activity | |
| 3-hydroxybutyrate dehydrogenase activity |
| GO Cellular Component | mitochondrion |
|---|---|
| mitochondrial matrix | |
| mitochondrial inner membrane |
| GO Biological Process | metabolic process |
|---|---|
| oxidation reduction |
| Group | mitochondrion |
|---|---|
| mitochondrial matrix | |
| mitochondrial inner membrane | |
| binding | |
| catalytic activity | |
| oxidoreductase activity | |
| 3-hydroxybutyrate dehydrogenase activity | |
| metabolic process | |
| oxidation reduction |
| Hugo ID | 1027 |
|---|
| Human chromosome position | 3q29 |
|---|
| LocusLink ID | 622 |
|---|---|
| 71911 | |
| 117099 |
| Alias | BDH |
|---|---|
| SDR9C1 | |
| MGC2723 | |
| MGC4347 | |
| MGC9788 | |
| 3-hydroxybutyrate dehydrogenase, type 1 | |
| (R)-3-hydroxybutyrate dehydrogenase | |
| D-beta-hydroxybutyrate dehydrogenase, mitochondrial | |
| 3-hydroxybutyrate dehydrogenase (heart, mitochondrial) | |
| short chain dehydrogenase/reductase family 9C, member 1 | |
| AI327223 | |
| 2310032J20Rik | |
| OTTMUSP00000031602 | |
| OTTMUSP00000031603 | |
| OTTMUSP00000031604 | |
| b-hydroxybutyrate dehydrogenase | |
| D-beta-hydroxybutyrate dehydrogenase | |
| MGC94818 | |
| 3- hydroxybutyrate dehydrogenase | |
| mitochondrial D-beta-hydroxybutyrate dehydrogenase | |
| hydroxybutyrate oxidoreductase | |
| mitochondrial 3-hydroxybutyrate dehydrogenase (heart) | |
| D-beta-hydroxybutyrate dehydrogenase precursor | |
| beta-hydroxybutyrate dehydrogenase | |
| beta-hydroxybutyric dehydrogenase | |
| D-(-)-3-hydroxybutyrate dehydrogenase | |
| NAD-beta-hydroxybutyrate dehydrogenase | |
| 3-D-hydroxybutyrate dehydrogenase | |
| beta-hydroxybutyric acid dehydrogenase | |
| beta-hydroxybutyric acid dehydrogenases | |
| 3-D-hydroxybutyrate dehydrogenases | |
| beta-hydroxybutyrate dehydrogenases | |
| beta-hydroxybutyric dehydrogenases | |
| D-(-)-3-hydroxybutyrate dehydrogenases | |
| hydroxybutyrate oxidoreductases | |
| NAD-beta-hydroxybutyrate dehydrogenases | |
| bdh1 | |
| 3-hydroxybutyrate dehydrogenase |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 603063 |
|---|
| Swiss-Prot Accession | Q02338 |
|---|---|
| Q3UL45 | |
| Q80XN0 | |
| P29147 |
| Unigene ID | Hs.274539 |
|---|---|
| Mm.293470 | |
| Rn.36635 |
| KEGG ID | hsa:622 |
|---|---|
| rno:117099 |
| EC Number | 1.1.1.30 |
|---|
| Swiss-Prot ID | BDH_HUMAN |
|---|---|
| BDH_RAT | |
| Q3UL45_MOUSE |
| GO ID | 0003858 |
|---|---|
| 0005488 | |
| 0016491 | |
| 0055114 | |
| 0005743 | |
| 0005759 | |
| 0005739 | |
| 0003824 | |
| 0008152 |
| IPI ID | IPI00025341 |
|---|---|
| IPI00794146 | |
| IPI00794690 | |
| IPI00792857 | |
| IPI00330754 | |
| IPI00890322 | |
| IPI00857778 | |
| IPI00480620 |
| Mouse chromosome position | 16 B2 |
|---|
| Homologene ID | 20860 |
|---|
| MGI ID | 1919161 |
|---|
| Rat chromosome position | 11q22 |
|---|
| RGD ID | 620131 |
|---|