| URN | urn:agi-llid:27108 |
|---|---|
| Connectivity | 7 |
| Name | Mat2b |
| Description | methionine adenosyltransferase II, beta |
| Notes | The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq] |
| Pathway | methionine cycle/metabolic pathway |
|---|---|
| methionine cycle-metabolic pathway |
| GO Molecular Function | catalytic activity |
|---|---|
| methionine adenosyltransferase regulator activity | |
| dTDP-4-dehydrorhamnose reductase activity |
| GO Cellular Component | intracellular |
|---|---|
| methionine adenosyltransferase complex | |
| mitochondrion | |
| nucleus |
| GO Biological Process | metabolic process |
|---|---|
| one-carbon metabolic process | |
| S-adenosylmethionine biosynthetic process | |
| extracellular polysaccharide biosynthetic process |
| Ariadne Ontology | Asp-Lys-Thr-Met-Cys metabolsm |
|---|
| Group | Asp-Lys-Thr-Met-Cys metabolsm |
|---|---|
| catalytic activity | |
| metabolic process | |
| one-carbon metabolic process | |
| S-adenosylmethionine biosynthetic process | |
| extracellular polysaccharide biosynthetic process | |
| methionine adenosyltransferase regulator activity | |
| dTDP-4-dehydrorhamnose reductase activity | |
| intracellular | |
| methionine adenosyltransferase complex | |
| mitochondrion | |
| nucleus |
| MedScan ID | 27108 |
|---|
| Hugo ID | 6905 |
|---|
| Human chromosome position | 5q34-q35 |
|---|
| LocusLink ID | 27108 |
|---|---|
| 27430 | |
| 108645 | |
| 683630 |
| Alias | TGR |
|---|---|
| MAT-II | |
| SDR23E1 | |
| MGC12237 | |
| MATIIbeta | |
| Nbla02999 | |
| MSTP045 | |
| methionine adenosyltransferase 2 subunit beta | |
| MAT II beta | |
| putative protein product of Nbla02999 | |
| dTDP-4-keto-6-deoxy-D-glucose 4-reductase | |
| short chain dehydrogenase/reductase family 23E, member 1 | |
| beta regulatory subunit of methionine adenosyltransferase | |
| AI182287 | |
| AU022853 | |
| 1110064C04Rik | |
| 2410018D16Rik | |
| RP23-382C18.2 | |
| OTTMUSP00000005600 | |
| methionine adenosyltransferase 2 beta subunit | |
| MGC94725 | |
| 1110064C04 | |
| 2410018D16 | |
| MAT2B | |
| methionine adenosyltransferase II, beta |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 605527 |
|---|
| Mouse chromosome position | 11 |
|---|
| GO ID | 0003824 |
|---|---|
| 0008831 | |
| 0048270 | |
| 0006556 | |
| 0045226 | |
| 0008152 | |
| 0006730 | |
| 0005622 | |
| 0048269 | |
| 0005739 | |
| 0005634 |
| Rat chromosome position | 10 |
|---|
| Swiss-Prot Accession | Q9NZL9 |
|---|---|
| Q99LB6 | |
| Q5U2R0 | |
| B2R5Y6 | |
| Q1WAI7 | |
| Q27J92 | |
| Q3LIE8 | |
| Q567T7 | |
| Q6NYC7 | |
| Q9BS89 | |
| Q9H3E1 | |
| Q9UJ54 | |
| Q5NC89 | |
| Q76LX2 | |
| Q8BVX6 | |
| Q8BYT9 |
| Unigene ID | Hs.54642 |
|---|---|
| Mm.293771 | |
| Rn.1752 |
| KEGG ID | hsa:27430 |
|---|---|
| mmu:108645 | |
| rno:683630 |
| EC Number | 2.5.1.6 |
|---|
| Swiss-Prot ID | MAT2B_HUMAN |
|---|---|
| MAT2B_RAT | |
| MAT2B_MOUSE | |
| B2R5Y6_HUMAN |
| Cell Localization | Cytoplasm |
|---|
| IPI ID | IPI00002324 |
|---|---|
| IPI00181717 | |
| IPI00845294 | |
| IPI00845444 | |
| IPI00845510 | |
| IPI00198904 | |
| IPI00468802 | |
| IPI00649402 | |
| IPI00874248 | |
| IPI00459789 | |
| IPI00786804 |
| Homologene ID | 8323 |
|---|
| RGD ID | 1593534 |
|---|
| MGI ID | 1913667 |
|---|