Ariadne Genomics Inc. S-adenosylmethioninamine ---> methylthioadenosine dimethylglycine ---| Bhmt Srm Sms polyamine metabolic pathway S-adenosylmethionine ---> S-adenosylhomocysteine AdoMet-dependent methyltransferases betaine 5-methyl-THF THF dimethylglycine homocysteine methylthioadenosine spermine metabolic pathway methyl group transfer to carbon, nitrogen, oxygen or sulfur atoms on proteins, nucleic acids, carbohydrates, lipids, small molecules Cbl ATP ---> S-adenosylmethionine methylthioadenosine ---> 1-phosphomethylthioribose AdoMet radical reactions involved in co-factor and other natural products biosynthesis in anaerobic organisms S-adenosylmethionine ---> S-adenosylmethioninamine spermidine metabolic pathway Mtap S-adenosylmethioninamine 1-phosphomethylthioribose ATP methionine adenosine Mtrr ---> Mtr Mtrr Mat2b ---> Mat2a Mat2b folate cycle metabolic pathway Amd1 S-adenosylhomocysteine ---| AdoMet-dependent methyltransferases homocysteine metabolic pathway diet ---> methionine diet 5-methyl-THF ---> THF adenosine <--> S-adenosylhomocysteine Ahcy Mat2a Mat1a 1-phosphomethylthioribose ---> methionine methionine ---> protein biosynthesis protein biosynthesis methionine ---> S-adenosylmethionine S-adenosylmethionine ---> AdoMet radical reactions involved in co-factor and other natural products biosynthesis in anaerobic organisms Mtr homocysteine <--> S-adenosylhomocysteine folate mediated one-carbon metabolic pathway homocysteine ---> methionine Bhmt betaine ---> dimethylglycine S-adenosylhomocysteine S-adenosylmethionine