Protein Rpia

URN urn:agi-llid:22934
Total Entities 0
Connectivity 34
Name Rpia
Description ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
Notes The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010]

GO Molecular Function isomerase activity
ribose-5-phosphate isomerase activity
carbohydrate binding
monosaccharide binding

GO Cellular Component intracellular
cytosol
intracellular membrane-bounded organelle

GO Biological Process small molecule metabolic process
pentose-phosphate shunt
pentose-phosphate shunt, non-oxidative branch
ribose phosphate metabolic process
carbohydrate metabolic process

Pathway pentose phosphate pathway
pentose phosphate pathway

Group Pentose-phosphate shunt
small molecule metabolic process
pentose-phosphate shunt
pentose-phosphate shunt, non-oxidative branch
isomerase activity
ribose-5-phosphate isomerase activity
ribose phosphate metabolic process
carbohydrate metabolic process
carbohydrate binding
monosaccharide binding
intracellular
cytosol
intracellular membrane-bounded organelle
Biofluids assayable substances

LocusLink ID 22934
19895
362383

Cell Localization Cytoplasm

GO ID 0048029
0004751
0005975
0006098
0009052
0019693
0044281
0005829
0005622
0043231
0030246
0016853
0005529
0005792
0005625

Alias RPI
ribose-5-phosphate isomerase
phosphoriboisomerase
ribose 5-phosphate epimerase
OTTMUSP00000026232
Rpia
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
ribose 5-phosphate isomerase A
RIBOSE 5-PHOSPHATE ISOMERASE

Mouse chromosome position 6 32.06 cM
6 30.0 cM

OMIM ID 180430
608611

Rat chromosome position 4q32

Hugo ID 10297

Human chromosome position 2p11.2

Swiss-Prot Accession P49247
P47968
D4A7L6
Q541P9
Q96BJ6
Q3UVI8

PIR ID I53951

GenBank ID NC_000002
NM_144563
NP_653164
NG_016710
NC_018913
AC_000134
ABBA01018821
AC062029
AAY14778
AC096579
AAY24200
AC244205
CH471215
EAW77066
EAW77067
AY050633
AAK95569
BC015529
AAH15529
BF063086
CB989690
L35035
P49247
NC_000072
NM_009075
NP_033101
AC_000028
AAHY01054150
AC153612
AC156398
CH466523
EDK98925
AK137235
BAE23281
AK148291
BC053526
AAH53526
CO043650
L35034
AAC42060
P47968
NC_005103
NM_001108632
NP_001102102
XM_006236628
XP_006236690
AC_000072
AABR06031438
AAHX01030742
CH473957
EDL90977
NT_022184
NW_927808
NW_001838785
AC_000045
CR591516
CR592299
CR597054
CR599007
CR613216
CR620468
CR621693
CR624462
Q53R32
Q53SB2
NT_039353
NW_001030811
XM_342707
XP_342708
NW_001084830
XM_001062107
XP_001062107
NW_047693

Unigene ID Hs.469264
Mm.17905
Rn.12446

KEGG ID hsa:22934
mmu:19895
rno:362383

Swiss-Prot ID RPIA_HUMAN
RPIA_MOUSE

EC Number 5.3.1.6

Ensembl ID ENSG00000153574
ENSP00000283646
ENST00000283646
ENSMUSG00000053604
ENSMUSP00000064158
ENSMUST00000066134
ENSRNOG00000005576
ENSRNOP00000007927
ENSRNOT00000007927

Homologene ID 6943

Organism Homo sapiens
Mus musculus
Rattus norvegicus

MGI ID 103254

RGD ID 1311377

MedScan ID 22934