| URN | urn:agi-llid:23551 |
|---|---|
| Total Entities | 0 |
| Connectivity | 117 |
| Name | Rasd2 |
| Description | RASD family, member 2 |
| Notes | This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades. [provided by RefSeq, Jul 2008] |
| GO Molecular Function | GTPase activity |
|---|---|
| phosphatidylinositol 3-kinase binding | |
| G-protein beta-subunit binding | |
| ubiquitin conjugating enzyme binding | |
| nucleotide binding | |
| GTP binding |
| GO Cellular Component | membrane |
|---|---|
| plasma membrane |
| GO Biological Process | GTP catabolic process |
|---|---|
| signal transduction | |
| small GTPase mediated signal transduction | |
| regulation of cAMP-mediated signaling | |
| positive regulation of protein kinase B signaling | |
| synaptic transmission, dopaminergic | |
| behavior | |
| locomotory behavior | |
| positive regulation of protein sumoylation | |
| negative regulation of protein ubiquitination |
| Pathway | Huntington disease pathway |
|---|
| Group | GTP catabolic process |
|---|---|
| GTPase activity | |
| signal transduction | |
| small GTPase mediated signal transduction | |
| regulation of cAMP-mediated signaling | |
| positive regulation of protein kinase B signaling | |
| synaptic transmission, dopaminergic | |
| behavior | |
| locomotory behavior | |
| positive regulation of protein sumoylation | |
| negative regulation of protein ubiquitination | |
| phosphatidylinositol 3-kinase binding | |
| G-protein beta-subunit binding | |
| ubiquitin conjugating enzyme binding | |
| nucleotide binding | |
| GTP binding | |
| membrane | |
| plasma membrane |
| LocusLink ID | 23551 |
|---|---|
| 75141 | |
| 171099 |
| Cell Localization | Cell membrane |
|---|
| GO ID | 0031681 |
|---|---|
| 0005525 | |
| 0003924 | |
| 0043548 | |
| 0031624 | |
| 0007626 | |
| 0031397 | |
| 0051897 | |
| 0033235 | |
| 0043949 | |
| 0007264 | |
| 0001963 | |
| 0005886 | |
| 0000166 | |
| 0006184 | |
| 0007610 | |
| 0007165 | |
| 0016020 |
| Alias | Rhes |
|---|---|
| TEM2 | |
| MGC:4834 | |
| GTP-binding protein Rhes | |
| tumor endothelial marker 2 | |
| Ras homolog enriched in striatum | |
| TEM-2 | |
| AU045414 | |
| 4930526B11Rik | |
| SE6C | |
| RASD family, member II | |
| tumour endothelial marker 2 | |
| tumor endothelial marker II | |
| tumour endothelial marker II | |
| RASD family, member IIs | |
| 4930526B11 | |
| LOC234437 | |
| RASD family, member 2 |
| Mouse chromosome position | 8 |
|---|
| OMIM ID | 612842 |
|---|
| Rat chromosome position | 19p11 |
|---|
| Hugo ID | 18229 |
|---|
| Human chromosome position | 22q13.1 |
|---|
| Swiss-Prot Accession | Q96D21 |
|---|---|
| P63032 | |
| P63033 | |
| O95520 | |
| Q5THY8 | |
| Q9WVD3 |
| Unigene ID | Hs.474711 |
|---|---|
| Mm.179267 | |
| Rn.115571 |
| KEGG ID | hsa:23551 |
|---|---|
| mmu:75141 | |
| rno:171099 |
| Swiss-Prot ID | RHES_HUMAN |
|---|---|
| RHES_RAT | |
| RHES_MOUSE |
| Ensembl ID | ENSG00000100302 |
|---|---|
| ENSP00000216127 | |
| ENST00000216127 | |
| ENSMUSG00000034472 | |
| ENSMUSP00000118070 | |
| ENSMUST00000139848 | |
| ENSRNOG00000014761 | |
| ENSRNOP00000020017 | |
| ENSRNOT00000020017 |
| Homologene ID | 8628 |
|---|
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MGI ID | 1922391 |
|---|
| RGD ID | 628594 |
|---|
| MedScan ID | 23551 |
|---|