RGD Disease Portals

RGD disease portals are designed to be entry points for researchers to access data and tools related to their area of interest.  For a video tour of RGD’s Disease Portals, click on the “Disease Portals Tutorial” link below.

To download a complete set of disease ontology (DO) annotations for rat, mouse and/or human genes, rat and/or human QTL or rat strains, click here to access the RGD ftp site's "annotated RGD objects by ontology" directory and choose the tab-delimited text file you are interested in.  For files that include the ontology terms themselves in addition to ontology IDs choose the "with terms" folder and select the appropriate file in that directory.

 

    Renal Disease Portal                   

The Renal Disease Portal is an integrated resource for information on genes, QTLs and strains associated with a variety of kidney and renal system conditions such as Renal Hypertension, Polycystic Kidney Disease and Renal Insufficiency, as well as Kidney Neoplasms. On the front page, view data for all renal disease states or refine your selection using a pull-down list of diseases. A single click on a disease will provide a summary of the associated genes, QTLs, and strains. The GViewer image gives a genome-wide view of human, rat and mouse data, and color-coded synteny maps allow comparison between species. Lists of objects annotated to the selected disease category and/or term are linked to comprehensively curated RGD records providing additional functional and genomic annotation. The Renal Disease Portal also provides one-click access to data on Phenotypes, Pathways and Biological Processes associated with renal diseases.  Tools, Related Links and Rat Strain Models pages link to additional resources of interest to renal disease researchers. 


    Cancer Portal

 The Cancer Disease Portal is an integrated resource for information on genes, QTLs and strains associated with cancer.  The portal provides easy acces to data related to Breast. Biliary, Pancreatic, Urogenital and Kidney Cancers.  On the front page, view the results for all the included cancers or choose a disease category to get a pull-down list of diseases. A single click on a disease will provide a list of related genes, QTLs, and strains as well as a genome wide view of these via the GViewer tool.  A link from GViewer to GBrowse shows the genes and QTLs within their genomic context.  Additional pages for Phenotypes, Pathways and Biological Processes provide one-click access to data related to cancer.  Tools, Related Links and Rat Strain Models pages link to additional resources of interest to cancer researchers.

 

    Cardiovascular Disease Portal

RGD has released its Cardiovascular Disease Portal to provide researchers with easy access to data on genes, QTLs, strain models, biological processes and pathways related to cardiovascular diseases. This resource funded by NHLBI also includes dynamic data analysis tools to make it a one stop resource for cardiovascular researchers. The user chooses a disease category to get a pull-down list of diseases. A single click on a disease will provide a list of related genes, QTLs, and strains as well as a genome wide view of these across the genome via GViewer and access to GBrowse results showing the genes and QTLs within the genomic context. Additional pages for Biological Processes, Pathways and Phenotypes provide one-click access to data of interest. A Tools section and a Links section provide additional resources. 


    Diabetes Portal

 The Diabetes Disease Portal is an integrated resource for information on genes, QTLs and strains associated with diabetes.  The portal provides easy acces to data related to both Type 1 and Type 2 Diabetes and Diabetes-related Obesity and Hypertension, as well as information on Diabetic Complications.  On the front page, view the results for all the included diabetes-related disease states or choose a disease category to get a pull-down list of diseases. A single click on a disease will provide a list of related genes, QTLs, and strains as well as a genome wide view of these via the GViewer tool.  A link from GViewer to GBrowse shows the genes and QTLs within their genomic context.  Additional pages for Phenotypes, Pathways and Biological Processes provide one-click access to data related to diabetes.  Tools, Related Links and Rat Strain Models pages link to additional resources of interest to diabetes researchers.

 

    Immune and Inflammatory Disease Portal 

The Immune and Inflammatory Disease Portal is an integrated resource for information on genes, QTLs and strains associated with a variety of immune system afflictions such as Autoimmune Diseases and Immunoproliferative Disorders, as well as diseases involving Infection and Inflammation. On the front page, view data for all immune/inflammatory disease states or refine your selection using a pull-down list of diseases. A single click on a disease will provide a summary of the associated genes, QTLs, and strains. The GViewer image gives a genome-wide view of human, rat and mouse data, and color-coded synteny maps allow comparison between species. Lists of objects annotated to the selected disease term are linked to comprehensively curated RGD records providing additional functional and genomic annotation. The Immune & Inflammatory Disease Portal also provides one-click access to data on Phenotypes, Pathways and Biological Processes associated with immune/inflammatory diseases.  Tools, Related Links and Rat Strain Models pages link to additional resources of interest to immune/inflammatory disease researchers. 


    Neurological Disease Portal

RGD has released its Neurological Disease Portal to provide researchers with easy access to data on genes, QTLs, strain models, biological processes and pathways related to neurological diseases. This resource, partially funded by NINDS also includes dynamic data analysis tools to make it a one stop resource for neuroscience researchers. The user chooses a disease category to get a pull-down list of diseases. A single click on a disease will provide a list of related genes, QTLs, and strains as well as a genome wide view of these across the genome via GViewer and access to GBrowse results showing the genes and QTLs within the genomic context. Additional pages for Biological Processes, Pathways and Phenotypes provide one-click access to data of interest.  Tools, Strain Models and  Links sections provide additional resources. 


     Obesity / Metabolic Syndrome Portal

RGD has released its Obesity/Metabolic Syndrome Disease Portal to provide researchers with easy access to data on genes, QTLs, strain models, biological processes and pathways related to obesity diseases. The user chooses a disease category to get a pull-down list of diseases. A single click on a disease will provide a list of related genes, QTLs, and strains as well as a genome wide view of these across the genome via GViewer and access to GBrowse results showing the genes and QTLs within the genomic context. Additional pages for Biological Processes, Pathways and Phenotypes provide one-click access to data of interest. A Tools section and a Links section provide additional resources.

 

    Respiratory Disease Portal                   

The Respiratory Disease Portal is an integrated resource for information on genes, QTLs and strains associated with a variety of respiratory diseases.  This portal provides easy access to data related to conditions such as Asthma, COPD, Cystic Fibrosis and more.   On the front page, view the results for all the included respiratory disease states, or choose a general disease category to get a pull-down list of more specific diseases. A single click on a disease term will provide a list of related genes, QTLs, and strains as well as a genome wide view of these via the GViewer tool.  A link from GViewer to GBrowse shows the genes and QTLs within their genomic context.  Additional pages for Phenotypes, Pathways and Biological Processes provide one-click access to data related to respiratory diseases.  Tools, Related Links and Rat Strain Models pages link to additional resources of interest to researchers working on respiratory disease. 


  Disease Portals Tutorial