08/22/2016 - RGD publishes a new interactive diagram page for the fibrinolysis pathway

Fibrinolysis pathway

The fibrinolytic pathway is activated by fibrin clots. Coagulation, anticoagulant systems and fibrinolysis pathways coordinate to maintain proper hemostasis. The main component of fibrinolysis is plasmin – the active form of plasminogen (PLG). Plasmin processing of fibrin leads to dissolution of clots. Several inhibitory systems are in place to tightly regulate fibrinolysis. Click here to explore this important regulatory system.