Adenosine Monophosphate-Activated Protein Kinase (AMPK) Signaling Pathway | Hexosamine Biosynthetic Pathway | Pentose Phosphate Pathway | ||
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The AMPK Signaling Pathway is a fuel sensor which regulates ATP production in various tissues. Click here to explore this important pathway regarded as a possible therapeutic target for type 2 diabetes, obesity and metabolic syndrome. |
Perturbations of the Hexosamine Biosynthetic Pathway have been found to be associated with insulin resistance, glucose toxicity and other complications of diabetes. Click here to explore this important metabolic and signaling pathway. | The Pentose Phosphate Pathway represents an alternate route of glucose oxidation. Click here to explore this vital source of building blocks for fatty acid and cholesterol biosynthesis, cellular antioxidation and superoxide generation. |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.