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While many immune and inflammatory diseases are not subject to the intensive research of more prevalent afflictions, they can occur more often in children, frequently with lifelong consequences. To underscore their importance, treatment of these diseases has resulted in a pharmaceutical marketplace that approaches 100 billion dollars. Understanding the importance of research into immune and inflammatory diseases and the vital role that rat research plays in elucidating the relationship between the immune system and inflammation in the disease process, RGD has just released a new Disease Portal for immune and inflammatory disease. RGD's Immune & Inflammatory Disease Portal is an integrated resource for information on genes, QTLs and strains associated with a variety of immune system afflictions such as autoimmune diseases and immunoproliferative disorders, as well as diseases involving infection and inflammation. On the front page, view data for all immune/inflammatory disease states or refine your selection using a pull-down list of diseases. A single click on a disease will provide a summary of the associated genes, QTLs, and strains. The GViewer image gives a genome-wide view of human, rat and mouse data, and color-coded synteny maps allow comparison between species. Lists of objects annotated to the selected disease term are linked to comprehensively curated RGD records providing additional functional and genomic annotation. The Immune & Inflammatory Disease Portal also provides one-click access to data on Phenotypes, Biological Processes and Pathways associated with immune/inflammatory diseases. Tools, Related Links and Rat Strain Models pages link to additional resources of interest to immune/inflammatory disease researchers. Click here to explore the Immune & Inflammatory Disease Portal, or click here for access to all of RGD's Disease Portals. |
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