03/02/2015 - RGD publishes an interactive diagram page for the mRNA nuclear export pathway

mRNA nuclear export pathway

Mature mRNA that has been 5’-capped, spliced and 3’-polyadenylated has to be exported to the cytoplasm to serve as the template for protein biosynthesis. Its transport through the nuclear pore complex (NPC) is an important element of regulated gene expression. Nuclear export is dependent upon transport receptors and the adaptors that couple them to cargo.  Click here to explore this important regulatory pathway.