miRNAs (microRNAs) have emerged as important regulators of gene expression primarily acting as translational repressors. In addition, aberrant expression of miRNAs themselves has been associated with cancer; deletion, down- or up-regulation of particular miRNA genes appears to link to distinct types of cancer [see PMID 20422339]. Several differentially-expressed genes in human colorectal tumors are listed with links to their entries in RGD and miRBase. For more information check PMIDs  19912656, 19497386 and references therein.  [Some equivalent rat and mouse miRNAs can also be found at RGD and miRBase].

Downregulated
MIR34A – RGD, miRBase
MIR34B – RGD, miRBase
MIR34C – RGD, miRBase
MIR126 – RGD, miRBase
MIR143 – RGD, miRBase
MIR145 – RGD, miRBase

Upregulated
MIR21 – RGD, miRBase
MIR135A – RGD, miRBase
MIR135B – RGD, miRBase
17-92 cluster – a human genomic locus on chromosome 13q31.3 that encodes six miRNAs and that is amplified in several types of tumors [any of the six entries at miRBase provides links to the other five, the link from this page is to MIR17].