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Pathways

Nr3c1 chaperones

The chaperone and co-chaperone complex of the glucocorticoid receptor is essential for its proper functioning and turnover. For detailed information check PMID 16610357. The members of the chaperone machinery are listed with aliases in parentheses, full names and links to gene report pages:

Hsp90aa1 (Hsp90) – heat shock protein 90 alpha family class A member 1
Hsp90ab1 (Hsp84) – heat shock protein 90 alpha family class B member 1
Hspa4 (Hsp70) – heat shock protein family A member 4
Dnaja2 (Dj3, Cpr3, DjA2, Hirip4) – DnaJ heat shock protein family (Hsp40) member A2
Ptges3 (p23, Hsp90 co-chaperone) – prostaglandin E synthase 3
Stip2 (Hop, p60, STI1) – stress-induced phosphoprotein 1
Fkbp4 (FKBP52) – FK506 binding protein 4
Fkbp5 (AIG6, FKBP51) – FK506 binding protein 5
Ppid (CYPD, CYP-40, PPIase D, cyclophilin D) – peptidylprolyl isomerase D
Ppp5c (PP5) – protein phosphatase 5, catalytic subunit


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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.