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Gli targets

There are many target genes of Gli transcription factors, including components of the Hedgehog pathway itself. Several targets are listed with aliases in parentheses, full names and links to gene report pages:

Gli1 – GLI family zinc finger 1
Ptch1 (Ptch) – patched 1
Hhip – hedgehog-interacting protein
Bmp4 (Bmp-4) – bone morphogenetic protein 4
Fgf4 (Hst1) – fibroblast growth factor 4
Vegfa (Vegf) – vascular endothelial growth factor A
Ccnd1 (Prad1) – cyclin D1
Ccnd2 – cyclin D2
Bmi1 (Bmi1 polycomb ring finger oncogene) – BMI1 proto-oncogene, polycomb ring finger
Snai1 (Sna, SNAH, snail homolog 1 (Drosophila)) – snail family transcriptional repressor 1
Mycn (Nmyc, N-myc, Nmuc1, v-myc myelocytomatosis viral related oncogene, neuroblastoma dervied (avian)) – MYCN proto-oncogene, bHLH transcription factor

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.