4-OH-TAM CYPs

4-OH-TAM CYPs

The cytochrome P 450 phase I human enzymes involved in the conversion of tamoxifen to the 4-hydroxytamoxifen (4-OH-TAM) metabolite are listed with aliases in parentheses, full names and links to gene report pages (the main contributing enzyme in bold):

CYP2D6 (CYPD6, VYPIID6) – cytochrome P450 family 2 subfamily D member 6
CYP2C9 (CPC, CYPIIC9, P450IIC9) – cytochrome P450 family 2 subfamily C member 9
CYP2C19 (CYPIIC17, CYPIIC19) – cytochrome P450 family 2 subfamily C member 19
CYP2B6 (P450IIB1, CPB6) – cytochrome P450 family 2 subfamily B member 6

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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4-OH-TAM CYPs