Ontology Report – Annotations Help
What data is available in the ontolgy report
The “ONTOLOGY REPORT – ANNOTATIONS” page contains information about the term and links to objects annotated with the term. The topmost section summarizes information about the term itself. This is followed by a rat chromosome ideograms from Genome Viewer showing the positions of genetic objects annotated with the term. After the diagram, is a gene table listing genes annotated with the term. Lastly, the paths to the terms are listed together with an ontology tree at the bottom of the page.
Go to embedded Genome Viewer
Jump To…
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The Term is shown on top of the page followed by Accession, Definition and Synonyms. The Accession given here can be used for ontology general search to get the exact t ontology term. Synonyms includes names commonly used before standardization or other IDs used by different communities. The underlined terms or phrases in this section are links to further information of the term or phrase.
1 is a search box allowing users to perform another ontology search without leaving the report page. Search is initiated after enter or clicking the magnified lens within orange circle. Users may go back to the main ontology general search page by clicking the underlined phrase “go back to main search page.”
2 “ browse the term” is clickable on either the branch or the phrase underlined. This link will bring users to a center column where the ontology term is presented with parent terms and child terms on either side. |
3 Genome Viewer Diagram is the fully functional copy of the Genome Viewer (GViewer) embedded in the Ontology Report Page. This GViewer chromosome ideogram diagram displaying the genomic positions of all rat genetic objects annotated with the ontology term. These genetic objects –genes in dark red , qtls in blue- are shown to the right of each chromosome. The congenic chromosomal section of a rat strain is shown in green. |
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Click on a chromosome to open a zoom pane which gives a closer look at objects mapped to the selected area. One more clicking locks the slider in a fixed location. Links to the object report page are accessible by clicking on object symbols in the zoom pane.
To the right of zoom pane, there are four tabs allowing users to zoom in to have a closer look of chromosome region or zoom out to get a bird’s eye view of a bigger region. The “Send to GBrowse” tab will send the position information of selected chromosome region to the RGD Genome Browser (GBrowse). The full set of genes and /QTLs in the region of interest is displayed in GBrowse to give a more complete view of data in that area. |
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At the bottom of the GViewer diagram, there are four tabs on each side. To the left of diagram, the four tabs allowing users to view all objects, download objects, and add additional genomic objects to the diagram.
List All Objects
One mouse click on this tab will show a list of all the objects in the diagrams grouped by chromosomes. Clicking on the object will put the object and flanking chromosome regions in the zoom pane. |
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CSV export
One mouse click allows exporting the data objects as a CSV file. Users have the options of downloading all objects, objects shared by multiple searches or unique objects. |
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Add objects
This function allows overlaying additional objects to current GViewer diagram. One mouse click on this tab will bring up the window “Add objects to the Viewer.” Users have options to search for genes, QTLs, Markers or Ontology Terms and to display them in customized colors different from the existing objects in the current diagram. Click on one of the options will bring up the “Enter Keyword” window. Users can enter a search term for gene symbol, QTL symbol, marker symbol or an ontology term annotated to the bject of interest. .The example here is a QTL search with keyword “bp215” and brown color is picked for display. The search only returns with one QTL, Bp215. |
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Click on the symbol will show the object’ location along with other existing objects. Bp215 is colored yellow because it came up with both hypertension search and QTL keyword search. |
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All the objects annotated with the term are listed in the table below the Genome Viewer Diagram. The options of viewing one species (Rat, Mouse or Human) or All three species are on the top left corner. Unchecking the box next to “show annotations for the term’s descendants” will refresh the table and show only objects annotated to the exact term. The list can be sorted by any of the columns of data in the table. The object symbols are links to gene, QTL or strain report pages. The user can click on GBrowse symbol to go to the Genome Browser View of the object. In the Evidence column, evidence codes indicate the type of source used for the annotation. These are also links to more detailed information about the annotations. Evidence code definitions are given below. Under the Reference column are links to references from which the annotations were made. Each reference used in our curation process is assigned a RGD ID.
On the far right is a link to the ontology report page where users can view all annotations to the object. |
Experimental Evidence Codes
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